Evidence map›Paper›PMID 38736574›Full record

ArticleClinical case reports2024

Potential efficacy of crizanlizumab in treating priapism in sickle cell disease: A case report.

Mohammed Abdulgayoom, Mohammad S Afana, Awni Alshurafa, Mohamed A Yassin

Abstract readCase Reports
In one paragraph

Article in Clinical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mohammed AbdulgayoomDepartment of Hematology National Center for cancer care and Research, HMC Doha Qatar.ORCID https://orcid.org/0000-0003-0622-8455
Mohammad S AfanaDepartment of Hematology National Center for cancer care and Research, HMC Doha Qatar.
Awni AlshurafaDepartment of Hematology National Center for cancer care and Research, HMC Doha Qatar.
Mohamed A YassinDepartment of Hematology National Center for cancer care and Research, HMC Doha Qatar.ORCID https://orcid.org/0000-0002-1144-8076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This report documents the treatment of a 41-year-old male with sickle cell disease (SCD) and repeated stuttering priapism using crizanlizumab, which alleviated the priapism but induced a significant vaso-occlusive crisis during the second infusion. Encouragingly, no subsequent vaso-occlusive crises occurred. However, the potential for infusion-related adverse events warrants close supervision. Further research is necessary to explore its full benefits on priapism management.

Indexed as

acute chest syndromecrizanlizumabinfusion‐related reactionspain crisespriapismvaso‐occlusive crises

Identifiers

PMID38736574
PMCPMC11087216

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.