Evidence map›Paper›PMID 38735951›Full record

ArticleJournal of nanobiotechnology2024

A portable transistor immunosensor for fast identification of porcine epidemic diarrhea virus.

Xiao Hu, Mengjia Zhang, Yiwei Liu, Yu-Tao Li, Wentao Li, Tingxian Li, Jiahao Li, Xueqian Xiao, Qigai He, Zhi-Yong Zhang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao Hu *School of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, P.R. China.
Mengjia Zhang *National Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, P. R. China.
Yiwei LiuHunan Institute of Advanced Sensing and Information Technology, Xiangtan University, Hunan, 411105, P. R. China.
Yu-Tao LiSchool of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, P.R. China.
Wentao LiNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, P. R. China.
Tingxian LiKey Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics, School of Electronics, Peking University, Beijing, 100871, P. R. China.
Jiahao LiSchool of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, P.R. China.
Xueqian XiaoSchool of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, P.R. China.
Qigai HeNational Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, 430070, P. R. China. he628@mail.hzau.edu.cn.
Zhi-Yong ZhangKey Laboratory for the Physics and Chemistry of Nanodevices and Center for Carbon-based Electronics, School of Electronics, Peking University, Beijing, 100871, P. R. China. zyzhang@pku.edu.cn.
Guo-Jun ZhangSchool of Laboratory Medicine, Hubei University of Chinese Medicine, 16 Huangjia Lake West Road, Wuhan, 430065, P.R. China. zhanggj@hbtcm.edu.cn.

Funding

National Key Research and Development Program of China 2022YFB3204403
6 · The paper itself

Abstract

Widespread distribution of porcine epidemic diarrhea virus (PEDV) has led to catastrophic losses to the global pig farming industry. As a result, there is an urgent need for rapid, sensitive and accurate tests for PEDV to enable timely and effective interventions. In the present study, we develop and validate a floating gate carbon nanotubes field-effect transistor (FG CNT-FET)-based portable immunosensor for rapid identification of PEDV in a sensitive and accurate manner. To improve the affinity, a unique PEDV spike protein-specific monoclonal antibody is prepared by purification, and subsequently modified on FG CNT-FET sensor to recognize PEDV. The developed FET biosensor enables highly sensitive detection (LoD: 8.1 fg/mL and 10

Indexed as

Biosensing TechniquesNanotubes, CarbonPorcine epidemic diarrhea virusAnimalsAntibodies, MonoclonalAntibodies, ViralCoronavirus InfectionsEquipment DesignImmunoassayLimit of DetectionSpike Glycoprotein, CoronavirusSwineSwine DiseasesTransistors, ElectronicAntibodies, MonoclonalAntibodies, ViralNanotubes, CarbonSpike Glycoprotein, CoronavirusCarbon nanotubesField-effect transistorImmunosensorMonoclonal antibodyPorcine epidemic diarrhea virusSpike protein

Identifiers

PMID38735951
PMCPMC11089749

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.