Evidence map›Paper›PMID 38735933›Full record

ArticleJournal of nanobiotechnology2024

Taking SCFAs produced by Lactobacillus reuteri orally reshapes gut microbiota and elicits antitumor responses.

Nannan Li, Lili Niu, Yao Liu, Yang Wang, Xiaomin Su, Ce Xu, Zanya Sun, Huishu Guo, Jingru Gong, Shun Shen

Abstract read
In one paragraph

Article in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
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  7. Review
  8. Article
  9. Probiotics Cancer Interaction, Prevention, and Therapy.Immunity, inflammation and disease · 2026
    Review
  10. Cells · 2026
    Article
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  12. Review
  13. Article
  14. Article
  15. Synergistic effects ofmSystems · 2026
    Article
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  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Nannan Li *Central Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China.
Lili Niu *Central Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China.
Yao Liu *Pharmacy Department, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China.
Yang WangCentral Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China.
Xiaomin SuCentral Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China.
Ce XuCentral Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China.
Zanya SunCentral Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China.
Huishu GuoCentral Laboratory, First Affiliated Hospital, Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, 116021, China. guohuishu1@126.com.
Jingru GongPharmacy Department, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China. jingru_gong001@163.com.
Shun ShenPharmacy Department, Shanghai Pudong Hospital, Fudan University Pudong Medical Center, Shanghai, 201399, China. nanocarries@gmail.com.

Funding

Academic Leaders Training Program of Pudong Health Committee of Shanghai Grant No. PWRd 2022-09Scientific Research Project of Shanghai Pudong Hospital YJYJRC202106
6 · The paper itself

Abstract

backgroundColorectal cancer (CRC) incidence is increasing in recent years due to intestinal flora imbalance, making oral probiotics a hotspot for research. However, numerous studies related to intestinal flora regulation ignore its internal mechanisms without in-depth research.

resultsHere, we developed a probiotic microgel delivery system (L.r@(SA-CS)

conclusionIt appears that the oral administration of L.r@(SA-CS)

Indexed as

Fatty Acids, VolatileGastrointestinal MicrobiomeLimosilactobacillus reuteriProbioticsAdministration, OralAlginatesAnimalsAntineoplastic AgentsApoptosisButyric AcidCell Line, TumorChitosanColorectal NeoplasmsHumansMiceMice, Inbred BALB CAlginatesAntineoplastic AgentsButyric AcidChitosanFatty Acids, VolatileMicrogelsReceptors, G-Protein-CoupledButyrateGPR109AIntestinal floraMicrogelSCFAs

Identifiers

PMID38735933
PMCPMC11089779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.