ArticlePlant cell reports2024
Crosstalk between melatonin and nitric oxide restrains Cadmium-induced oxidative stress and enhances vinblastine biosynthesis in Catharanthus roseus (L) G Don.
Article in Plant cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Machine learning-assisted meta-analysis reveals melatonin crosstalk regulating plant growth plasticity under heavy metal stress.Plant cell reports · 2026Pooled it
- Vinca Extract Infused Silk Fibroin Hydrogel for Treatment of Artificially Induced Diabetic Foot Ulcer in Murine Model.Cell biochemistry and biophysics · 2026Article
- From Abiotic Stress to Emerging Environmental Pollutants: Expanding Roles of Melatonin and NO in Plant Defense.International journal of molecular sciences · 2026Review
- Carbon quantum dots and mycorrhizal fungi improve cadmium stress tolerance and essential oil production in grapefruit mint (Mentha suaveolens × piperita).Scientific reports · 2026Article
- Exogenous melatonin enhances the tolerance of ground-cover Chrysanthemum morifolium Ramat. to cadmium by improving photosynthetic capacity and reactive oxygen species scavenging.Plant cell reports · 2026Article
- Dose-dependent effect of He-Ne laser on Pb tolerance and phytoremediation potential of milk Thistle (Silybum Marianum L.) Gaertn.BMC plant biology · 2025Article
- Foliar application of yeast extract mitigates water deficit stress and elicits hypericin and phenolic production in Hypericum perforatum L.Scientific reports · 2025Article
- Plant Secondary Metabolites-Central Regulators Against Abiotic and Biotic Stresses.Metabolites · 2025Review
- Elite genotype selection through antioxidant and antimicrobial activities, in vitro multiplication with3 Biotech · 2025Article
- Seed laser priming enhances defensive responses in milk thistle under Pb toxicity.Scientific reports · 2025Article
- Reactive oxygen and nitrogen species in plant defense mechanisms.Plant cell reports · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
key messageNitric oxide functions downstream of the melatonin in adjusting Cd-induced osmotic and oxidative stresses, upregulating the transcription of D4H and DAT genes, and increasing total alkaloid and vincristine contents. A few studies have investigated the relationship between melatonin (MT) and nitric oxide (NO) in regulating defensive responses. However, it is still unclear how MT and NO interact to regulate the biosynthesis of alkaloids and vincristine in leaves of Catharanthus roseus (L.) G. Don under Cd stress. Therefore, this context was explored in the present study. Results showed that Cd toxicity (200 µM) induced oxidative stress, decreased biomass, Chl a, and Chl b content, and increased the content of total alkaloid and vinblastine in the leaves. Application of both MT (100 µM) and sodium nitroprusside (200 µM SNP, as NO donor) enhanced endogenous NO content and accordingly increased metal tolerance index, the content of total alkaloid and vinblastine. It also upregulated the transcription of two respective genes (D4H and DAT) under non-stress and Cd stress conditions. Moreover, the MT and SNP treatments reduced the content of H
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