Evidence map›Paper›PMID 38735059›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2024

Kinetic modeling of the monoamine oxidase-B radioligand [

Brian J Lopresti, Jeffrey Stehouwer, Alexandria C Reese, Neale S Mason, Sarah K Royse, Rajesh Narendran, Charles M Laymon, Oscar L Lopez, Ann D Cohen, Chester A Mathis and 1 more

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Astrocyte reactivity across the AD continuum measured by [European journal of nuclear medicine and molecular imaging · 2026
    Article
  2. Article
  3. Complex interplay of astrogliosis and pathology in preclinical Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  4. Review
  5. Kinetic and quantitative analysis of [Annals of nuclear medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Brian J LoprestiDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Jeffrey StehouwerDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.ORCID 0000-0001-8871-2544
Alexandria C ReeseDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Neale S MasonDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Sarah K RoyseDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Rajesh NarendranDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Charles M LaymonDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Oscar L LopezDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Ann D CohenDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Chester A MathisDepartment of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Victor L VillemagneDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

Vascular Moderators of the Impact of Alzheimer's Pathology in the Young-OldP01AG025204 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOWARD J AIZENSTEIN, Ann D. Cohen · 2005 to 2026
$56.5M
NIA NIH HHS P01 AG025204
6 · The paper itself

Abstract

This paper describes pharmacokinetic analyses of the monoamine-oxidase-B (MAO-B) radiotracer [

Indexed as

Alzheimer DiseaseBrainMonoamine OxidasePositron-Emission TomographyRadiopharmaceuticalsAgedAged, 80 and overCognitive DysfunctionFemaleFluorine RadioisotopesHumansKineticsMaleMiddle AgedQuinolinesFluorine RadioisotopesMonoamine OxidaseQuinolinesRadiopharmaceuticalsAlzheimer’s diseaseastrogliosismonoamine oxidase-BneurodegenerationPositron emission tomography

Identifiers

PMID38735059
PMCPMC11542143

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.