Evidence map›Paper›PMID 38734995›Full record

ArticlePhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology2024

Photodynamic inactivation of E. coli with cationic imidazolyl-porphyrin photosensitizers and their synergic combination with antimicrobial cinnamaldehyde.

Madalena F C Silva, Rafael T Aroso, Janusz M Dabrowski, Barbara Pucelik, Agata Barzowska, Gabriela J da Silva, Luis G Arnaut, Mariette M Pereira

Abstract read
PubMed Publisher
In one paragraph

Article in Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. The Immunostimulatory Effect of MIL-101(Al)-NHInternational journal of molecular sciences · 2025
    Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Madalena F C SilvaDepartment of Chemistry, CQC-IMS, University of Coimbra, 3004-535, Coimbra, Portugal.
Rafael T ArosoDepartment of Chemistry, CQC-IMS, University of Coimbra, 3004-535, Coimbra, Portugal. rafaelaroso@uc.pt.ORCID http://orcid.org/0000-0002-2657-9212
Janusz M DabrowskiFaculty of Chemistry, Jagiellonian University, Gronostajowa 2, 30-387, Krakow, Poland. jdabrows@chemia.uj.edu.pl.ORCID http://orcid.org/0000-0002-8791-7035
Barbara PucelikMalopolska Center of Biotechnology, Jagiellonian University, Gronostajowa 7A, 30-387, Krakow, Poland.
Agata BarzowskaMalopolska Center of Biotechnology, Jagiellonian University, Gronostajowa 7A, 30-387, Krakow, Poland.
Gabriela J da SilvaFaculty of Pharmacy and Center for Neurosciences and Cell Biology, University of Coimbra, Azinhaga de Santa Comba, 3000-548, Coimbra, Portugal.
Luis G ArnautDepartment of Chemistry, CQC-IMS, University of Coimbra, 3004-535, Coimbra, Portugal.
Mariette M PereiraDepartment of Chemistry, CQC-IMS, University of Coimbra, 3004-535, Coimbra, Portugal. mmpereira@qui.uc.pt.ORCID http://orcid.org/0000-0003-4958-7677

Funding

Fundação para a Ciência e a Tecnologia PTDC/QUI-OUT/0303/2021Fundação para a Ciência e a Tecnologia UIDB/00313/2020Fundação para a Ciência e a Tecnologia UID/BIA/04004/2020Narodowe Centrum Nauki 2016/22/E/NZ7/00420PRR - Recovery and Resilience Plan and Next Generation EU Funds 6979 - PRODUTECH R3
6 · The paper itself

Abstract

Bacterial infections are a global health concern, particularly due to the increasing resistance of bacteria to antibiotics. Multi-drug resistance (MDR) is a considerable challenge, and novel approaches are needed to treat bacterial infections. Photodynamic inactivation (PDI) of microorganisms is increasingly recognized as an effective method to inactivate a broad spectrum of bacteria and overcome resistance mechanisms. This study presents the synthesis of a new cationic 5,15-di-imidazolyl porphyrin derivative and the impact of n-octanol/water partition coefficient (logP) values of this class of photosensitizers on PDI efficacy of Escherichia coli. The derivative with logP = -0.5, IP-H-OH

Indexed as

AcroleinAnti-Bacterial AgentsEscherichia coliImidazolesPhotosensitizing AgentsPorphyrinsAnimalsCationsDrug SynergismMiceMicrobial Sensitivity TestsPhotochemotherapyAcroleinAnti-Bacterial AgentsCationscinnamaldehydeImidazolesPhotosensitizing AgentsPorphyrinsCationic imidazolyl porphyrinsCinnamaldehydeDual therapyE. coliPhotodynamic inactivationPhotosensitizers

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.