Evidence map›Paper›PMID 38734789›Full record

ArticleScientific reports2024

Examining variations in body composition among patients with colorectal cancer according to site and disease stage.

Mayra Laryssa da Silva Nascimento, Nithaela Alves Bennemann, Iasmin Matias de Sousa, Mara Rubia de Oliveira Bezerra, Gabriela Villaça Chaves, Sara Maria Moreira Lima Verde, Silvia Fernandes Maurício, José Barreto Campello Carvalheira, Maria Carolina Santos Mendes, Ana Lucia Miranda and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. HyperSightRadiation oncology (London, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mayra Laryssa da Silva Nascimento *PesqClin Lab, Onofre Lopes University Hospital, Brazilian Company of Hospital Services (EBSERH), Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Nithaela Alves Bennemann *PesqClin Lab, Onofre Lopes University Hospital, Brazilian Company of Hospital Services (EBSERH), Federal University of Rio Grande do Norte, Natal, RN, Brazil.
Iasmin Matias de Sousa *Health Sciences Center, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, No 3000, Natal, RN, 59078-970, Brazil.
Mara Rubia de Oliveira BezerraHealth Sciences Center, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, No 3000, Natal, RN, 59078-970, Brazil.
Gabriela Villaça ChavesNational Institute of Cancer, Rio de Janeiro, RJ, Brazil.
Sara Maria Moreira Lima VerdeState University of Ceará, Fortaleza, CE, Brazil.
Silvia Fernandes MaurícioFederal University of Ouro Preto, Ouro Preto, MG, Brazil.
José Barreto Campello CarvalheiraDivision of Oncology, Department of Anesthesiology, Oncology and Radiology, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
Maria Carolina Santos MendesDivision of Oncology, Department of Anesthesiology, Oncology and Radiology, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, SP, Brazil.
Ana Lucia MirandaHealth Sciences Center, Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, No 3000, Natal, RN, 59078-970, Brazil.
Jarson Pedro da Costa PereiraDepartment of Nutrition, Federal University of Pernambuco, Recife, PE, Brazil.
M Cristina GonzalezFederal University of Pelotas, Pelotas, RS, Brazil.
Carla M PradoHuman Nutrition Research Unit, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada.
Ana Paula Trussardi FayhPesqClin Lab, Onofre Lopes University Hospital, Brazilian Company of Hospital Services (EBSERH), Federal University of Rio Grande do Norte, Natal, RN, Brazil. ana.fayh@ufrn.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

Patients with colorectal cancer (CRC) often exhibit changes in body composition (BC) which are associated with poorer clinical outcomes. Many studies group colon and rectal cancers together, irrespective of staging, potentially affecting assessment and treatment strategies. Our study aimed to compare BC in patients with CRC focusing on tumor location and metastasis presence. A total of 635 individuals were evaluated, with a mean age of 61.8 ± 12.4 years and 50.2% female. The majority had rectal cancer as the primary cancer site (51.0%), and 23.6% had metastatic disease. The first regression model showed tumor site and metastasis as independent factors influencing skeletal muscle (SM), skeletal muscle index (SMI), and visceral adipose tissue variability (all p values < 0.05). The second model, adjusted for BMI, indicated tumor site as the primary factor affecting SMI variations (adjusted R

Indexed as

Body CompositionColorectal NeoplasmsNeoplasm StagingAgedBody Mass IndexFemaleHumansIntra-Abdominal FatMaleMiddle AgedMuscle, Skeletal

Identifiers

PMID38734789
PMCPMC11088614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.