Evidence map›Paper›PMID 38734664›Full record

ArticleMalaria journal2024

Hesitancy towards R21/Matrix-M malaria vaccine among Ghanaian parents and attitudes towards immunizing non-eligible children: a cross-sectional survey.

Mohamed Fakhry Hussein, Frank Kyei-Arthur, Marina Saleeb, Sylvester Kyei-Gyamfi, Theophilus Abutima, Ignatius Great Sakada, Ramy Mohamed Ghazy

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In one paragraph

Article in Malaria journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mohamed Fakhry HusseinOccupational Health and Industrial Medicine Department, High Institute of Public Health, Alexandria University, Alexandria, 21561, Egypt. hiph-mohamedfakhry@alexu.edu.eg.ORCID http://orcid.org/0000-0003-3775-6226
Frank Kyei-ArthurDepartment of Environment and Public Health, the University of Environment and Sustainable Development, Somanya, Ghana.
Marina SaleebBiostatistics Department, MARS-GLOBAL, London, WC2H 9JQ, UK.
Sylvester Kyei-GyamfiDepartment of Children, Ministry of Gender, Children and Social Protection, Accra, Ghana.
Theophilus AbutimaDepartment of Sociology and Anthropology, University for Development Studies, Nyankpala Campus, Nyankpal, Ghana.
Ignatius Great SakadaDepartment of Population, Family and Reproductive Health, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Ramy Mohamed GhazyDepartment of Family and Community Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe newly developed malaria vaccine called "R21/Matrix-M malaria vaccine" showed a high safety and efficacy level, and Ghana is the first country to approve this new vaccine. The present study aimed to evaluate the rate of vaccine hesitancy (VH) towards the newly developed malaria vaccine among parents who currently have children who are not eligible for the vaccine but may be eligible in the near future. Additionally, the study aimed to identify the factors that could potentially influence VH.

methodsA cross-sectional survey using both online-based questionnaires and face-to-face interviews was conducted in Ghana from June to August 2023. The survey specifically targeted parents of ineligible children for vaccination, including those aged less than 5 months or between 3 and 12 years. The Parent Attitudes about Childhood Vaccination (PACV) scale was used to assess parental VH.

resultsA total of 765 people participated in this study. Their median age was 36.0 years with an interquartile range of 31.0-41.0 years, 67.7% were females, 41.8% completed their tertiary education, 63.3% were married, 81.6% worked in non-healthcare sectors, and 59.7% reported that their monthly income was insufficient. About one-third (34.5%) of the parents were hesitant to give their children the R21/Matrix-M malaria vaccine. The following predictors were associated with VH: working in the healthcare sector (adjusted odds ratio (AOR) = 0.50; 95% confidence interval (CI) 0.30-0.80; p = 0.005), having the other parent working in the healthcare sector (AOR = 0.54; 95% CI 0.30-0.94; p = 0.034), and not taking scheduled routine vaccinations (AOR = 1.90; 95% CI 1.27-2.84; p = 0.002).

conclusionsAddressing VH is crucial for optimizing R21/Matrix-M vaccine coverage in Ghana's malaria control strategy. By tackling VH issues, Ghana can effectively safeguard children's health in malaria-prone areas.

Indexed as

Malaria VaccinesParentsAdultChildChild, PreschoolCross-Sectional StudiesFemaleGhanaHumansInfantMalariaMaleMiddle AgedSurveys and QuestionnairesVaccinationVaccination HesitancyMalaria VaccinesGhanaHealth policy planningMalariaParent Attitudes about Childhood Vaccination ScaleR21/Matrix-M vaccineVaccine hesitancy

Identifiers

PMID38734664
PMCPMC11088762

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.