Evidence map›Paper›PMID 38734196›Full record

ArticlePhotodiagnosis and photodynamic therapy2024

Miniature wireless LED-device for photodynamic-induced cell pyroptosis.

Sunghoon Rho, Hailey S Sanders, Bradley D Smith, Thomas D O'Sullivan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Photodiagnosis and photodynamic therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sunghoon RhoDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46656, USA.
Hailey S SandersDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA.
Bradley D SmithDepartment of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address: smith.115@nd.edu.
Thomas D O'SullivanDepartment of Electrical Engineering, University of Notre Dame, Notre Dame, IN 46656, USA. Electronic address: tosullivan@nd.edu.

Funding

Molecular Probes for Biomembrane RecognitionR35GM136212 · NIGMS · UNIVERSITY OF NOTRE DAME · PI Bradley D Smith · 2020 to 2026
$2.5M
NIGMS NIH HHS R35 GM136212
6 · The paper itself

Abstract

The inability of visible light to penetrate far through biological tissue limits its use for phototherapy and photodiagnosis of deep-tissue sites of disease. This is unfortunate because many visible dyes are excellent photosensitizers and photocatalysts that can induce a wide range of photochemical processes, including photogeneration of reactive oxygen species. One potential solution is to bring the light source closer to the site of disease by using a miniature implantable LED. With this goal in mind, we fabricated a wireless LED-based device (volume of 23 mm

Indexed as

PhotochemotherapyPhotosensitizing AgentsPyroptosisRose BengalAnimalsHT29 CellsHumansWireless TechnologyPhotosensitizing AgentsRose BengalCell deathImplantable devicePhotodynamic therapyPyroptosisRose BengalWireless LED

Identifiers

PMID38734196
PMCPMC11336689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.