Evidence map›Paper›PMID 38733501›Full record

ArticleInternational urology and nephrology2024

Surgical intervention and long-term renal outcomes of congenital ureteropelvic junction obstruction in a young adult cohort.

Alexandra R Stewart, Stephen W Olson, Brent L Lechner, Maura A Watson, Christina M Yuan, Robert Nee

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Article in International urology and nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Alexandra R StewartNephrology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Stephen W OlsonNephrology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Brent L LechnerPediatric Nephrology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Maura A WatsonNephrology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Christina M YuanNephrology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA.
Robert NeeNephrology Service, Walter Reed National Military Medical Center, Bethesda, MD, USA. robert.nee.civ@health.mil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the impact of surgical intervention on long-term renal outcomes for adult patients with congenital ureteropelvic junction obstruction (UPJO).

methodsWe queried service members diagnosed with UPJO from the United States Military Health System electronic health records from 2005 to 2020. We assessed demographic, laboratory, radiology, surgical intervention, and outcome data. We evaluated the impact of surgical intervention on renal function based on the estimated glomerular filtration rate (eGFR), hypertension (HTN, defined as any prescription for blood pressure [BP] medication and/or average of two BP readings ≥ 130/80 mmHg more than 2 weeks apart), and changes in renal excretory function on radionuclide scans.

resultsWe identified 108 individuals diagnosed with congenital UPJO; mean follow-up of 7 years. Mean age at diagnosis was 25 years; 95% male; 69% White, 15% Black. At diagnosis, median BP was 130/78 mmHg and mean eGFR 93 ml/min/1.73m

conclusionSurgical intervention was not associated with significant differences in the long-term outcomes of kidney function and HTN prevalence in our young adult cohort. However, renal excretory function improved on radionuclide scans.

Indexed as

Kidney PelvisUreteral ObstructionAdultCohort StudiesFemaleGlomerular Filtration RateHumansKidneyMaleRetrospective StudiesTime FactorsTreatment OutcomeUrologic Surgical ProceduresYoung AdultCongenital anomalies of the kidney and urinary tract (CAKUT)Congenital ureteropelvic junction obstructionHypertensionKidney functionMilitary health systemPyeloplasty

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.