Evidence map›Paper›PMID 38732685›Full record

ArticlePolymers2024

High-Temperature Polylactic Acid Proves Reliable and Safe for Manufacturing 3D-Printed Patient-Specific Instruments in Pediatric Orthopedics-Results from over 80 Personalized Devices Employed in 47 Surgeries.

Grazia Chiara Menozzi, Alessandro Depaoli, Marco Ramella, Giulia Alessandri, Leonardo Frizziero, Adriano De Rosa, Francesco Soncini, Valeria Sassoli, Gino Rocca, Giovanni Trisolino

Abstract read
In one paragraph

Article in Polymers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Grazia Chiara MenozziUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0003-3216-8046
Alessandro DepaoliRizzoli Sicilia Department, IRCCS Istituto Ortopedico Rizzoli, 90011 Bagheria, Italy.ORCID 0009-0006-7368-4935
Marco RamellaUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-4197-2426
Giulia AlessandriDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0003-1586-4090
Leonardo FrizzieroDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.ORCID 0000-0003-4809-3536
Adriano De RosaDepartment of Industrial Engineering, Alma Mater Studiorum University of Bologna, 40136 Bologna, Italy.
Francesco SonciniUnit of Hygiene, Epidemiology and Emergency Management, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-7614-0275
Valeria SassoliPharmacy Service, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Gino RoccaUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0009-0006-3757-1212
Giovanni TrisolinoUnit of Pediatric Orthopedics and Traumatology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.ORCID 0000-0002-0361-9920

Funding

ASD Cernobbio 2010 2022/730827Italian Ministry of Health RCR2022 - 23682299
6 · The paper itself

Abstract

(1) Background: Orthopedic surgery has been transformed by 3D-printed personalized instruments (3DP-PSIs), which enhance precision and reduce complications. Hospitals are adopting in-house 3D printing facilities, using cost-effective methods like Fused Deposition Modeling (FDM) with materials like Polylactic acid (PLA) to create 3DP-PSI. PLA's temperature limitations can be overcome by annealing High-Temperature PLA (ann-HTPLA), enabling steam sterilization without compromising properties. Our study examines the in vivo efficacy of ann-HTPLA 3DP-PSI in pediatric orthopedic surgery. (2) Methods: we investigated safety and efficacy using ann-HTPLA 3DP-PSI produced at an "in-office" 3D-printing Point-of-Care (3DP-PoC) aimed at correcting limb deformities in pediatric patients. Data on 3DP-PSI dimensions and printing parameters were collected, along with usability and complications. (3) Results: Eighty-three ann-HTPLA 3DP-PSIs were utilized in 33 patients (47 bone segments). The smallest guide used measured 3.8 cm

Indexed as

3D-printingannealingFused Deposition Modelinghigh-temperature polylactic acidin vivoorthopedic surgerypatient-specific instrumentpediatricspolylactic acidsterilization

Identifiers

PMID38732685
PMCPMC11085401

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.