Evidence map›Paper›PMID 38732563›Full record

SynthesisNutrients2024

The Role of Diet in the Cardiovascular Health of Childhood Cancer Survivors-A Systematic Review.

Ruijie Li, Alan R Barker, Dimitris Vlachopoulos, Dewi Paris, Christina Schindera, Fabiën N Belle, Raquel Revuelta Iniesta

Abstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Childhood cancer and future cardiometabolic health.npj metabolic health and disease · 2026
    Review
  2. Observational
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ruijie LiChildren's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.ORCID 0009-0009-2621-1969
Alan R BarkerChildren's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.ORCID 0000-0001-8610-5417
Dimitris VlachopoulosChildren's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.
Dewi ParisChildren's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.
Christina SchinderaChildhood Cancer Research Group, Institute of Social and Preventive Medicine (ISPM), University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland.
Fabiën N BelleChildhood Cancer Research Group, Institute of Social and Preventive Medicine (ISPM), University of Bern, Mittelstrasse 43, 3012 Bern, Switzerland.ORCID 0000-0002-0037-4817
Raquel Revuelta IniestaChildren's Health & Exercise Research Centre (CHERC), Faculty of Health and Life Sciences, University of Exeter, Exeter EX1 2LU, UK.ORCID 0000-0002-5534-7146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChildhood cancer survivors (CCSs) face an increased risk of cardiovascular disease (CVD). This systematic review aims to provide the first synthesis of observational and interventional studies on the relationship between diet and cardiovascular health in CCSs.

methodsA comprehensive search was conducted for studies published between 1990 and July 2023 in PubMed, MEDLINE, CINAHL, Child Development & Adolescent Studies, and Cochrane Library. Eligible studies included observational and interventional studies examining the associations or effects of dietary factors on CVD incidence, cardiac dysfunction, or CVD risk factors in CCSs diagnosed before age 25 years.

resultsTen studies met the inclusion criteria (nine observational and one interventional). Collectively, they comprised 3485 CCSs (male, 1734; female, 1751). The outcomes examined across observational studies included characteristics of obesity, diabetes biomarkers, hypertension indicators, dyslipidaemia biomarkers, and metabolic syndrome. The evidence suggested that greater adherence to healthy diets was associated with lower body mass index, blood pressure, glucose, and triglycerides and higher high-density lipoprotein cholesterol. The 12-week lifestyle intervention study in childhood leukaemia survivors found no impact on obesity indicators.

conclusionThe review results indicate the potentially protective effects of healthy diets. However, the available research remains preliminary and limited, underscoring the need for more rigorous, adequately powered studies.

Indexed as

Cancer SurvivorsCardiovascular DiseasesAdolescentAdultChildDietDiet, HealthyFemaleHumansMaleNeoplasmsRisk FactorsYoung Adultcardiac dysfunctioncardiovascular disease risk factorscardiovascular diseaseschildhood cancer survivorsdietdiet recommendations

Identifiers

PMID38732563
PMCPMC11085214

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.