Evidence map›Paper›PMID 38732545›Full record

ReviewNutrients2024

Exploiting Natural Niches with Neuroprotective Properties: A Comprehensive Review.

Hind Moukham, Alessia Lambiase, Giovanni Davide Barone, Farida Tripodi, Paola Coccetti

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Acteoside exerts neuroprotective effects by preventing α-synuclein aggregation and oxidative stress in models of Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Article
  4. Black gas, bright future: HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Review
  5. Review
  6. Review
  7. Lion's Mane Mushroom (Nutrients · 2025
    Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hind MoukhamDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.
Alessia LambiaseDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0003-0937-137X
Giovanni Davide BaroneInstitute of Biology, University of Graz, Universitätsplatz 2, 8010 Graz, Austria.ORCID 0000-0001-9673-3599
Farida TripodiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0003-1246-979X
Paola CoccettiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, 20126 Milano, Italy.ORCID 0000-0001-5898-5883

Funding

National Recovery and Resilience Plan (NRRP) CN_00000033, CUP H43C22000530001National Recovery and Resilience Plan (NRRP) CUP H43C22000820001
6 · The paper itself

Abstract

Natural products from mushrooms, plants, microalgae, and cyanobacteria have been intensively explored and studied for their preventive or therapeutic potential. Among age-related pathologies, neurodegenerative diseases (such as Alzheimer's and Parkinson's diseases) represent a worldwide health and social problem. Since several pathological mechanisms are associated with neurodegeneration, promising strategies against neurodegenerative diseases are aimed to target multiple processes. These approaches usually avoid premature cell death and the loss of function of damaged neurons. This review focuses attention on the preventive and therapeutic potential of several compounds derived from natural sources, which could be exploited for their neuroprotective effect. Curcumin, resveratrol, ergothioneine, and phycocyanin are presented as examples of successful approaches, with a special focus on possible strategies to improve their delivery to the brain.

Indexed as

CurcuminNeurodegenerative DiseasesNeuroprotective AgentsResveratrolAgaricalesAnimalsBiological ProductsCyanobacteriaErgothioneineHumansMicroalgaePhycocyaninBiological ProductsCurcuminErgothioneineNeuroprotective AgentsPhycocyaninResveratrolAlzheimer’s disease (AD)curcumindelivery strategiesergothioneineneuroprotectionParkinson’s disease (PD)phycocyaninresveratrol

Identifiers

PMID38732545
PMCPMC11085272

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.