Evidence map›Paper›PMID 38732540›Full record

ArticleNutrients2024

Intestinal Barrier Impairment Induced by Gut Microbiome and Its Metabolites in School-Age Children with Zinc Deficiency.

Xiaoqi Chai, Xiaohui Chen, Tenglong Yan, Qian Zhao, Binshuo Hu, Zhongquan Jiang, Wei Guo, Ying Zhang

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaoqi ChaiSchool of Public Health, Lanzhou University, Lanzhou 730000, China.ORCID 0009-0004-0107-4252
Xiaohui ChenSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Tenglong YanSchool of Public Health, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0002-2424-0223
Qian ZhaoSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Binshuo HuSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Zhongquan JiangSchool of Public Health, Lanzhou University, Lanzhou 730000, China.
Wei GuoKey Laboratory of Animal Genetics, Breeding and Reproduction in the Plateau Mountainous Region, Ministry of Education, Guizhou University, Guiyang 550000, China.
Ying ZhangSchool of Public Health, Lanzhou University, Lanzhou 730000, China.ORCID 0000-0003-1116-8290

Funding

Chinese Nutrition Society CNS-ZD2019008National Natural Science Foundation of China 82173497
6 · The paper itself

Abstract

Zinc deficiency affects the physical and intellectual development of school-age children, while studies on the effects on intestinal microbes and metabolites in school-age children have not been reported. School-age children were enrolled to conduct anthropometric measurements and serum zinc and serum inflammatory factors detection, and children were divided into a zinc deficiency group (ZD) and control group (CK) based on the results of serum zinc. Stool samples were collected to conduct metagenome, metabolome, and diversity analysis, and species composition analysis, functional annotation, and correlation analysis were conducted to further explore the function and composition of the gut flora and metabolites of children with zinc deficiency. Beta-diversity analysis revealed a significantly different gut microbial community composition between ZD and CK groups. For instance, the relative abundances of

Indexed as

FecesGastrointestinal MicrobiomeZincBacteriaChildFemaleHumansIntestinal MucosaIntestinesMaleMetabolomeZincintestinal microbiotametabolitesschool-age childrenzinc deficiency

Identifiers

PMID38732540
PMCPMC11085614

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.