Evidence map›Paper›PMID 38732533›Full record

ReviewNutrients2024

The Benefits of the Mediterranean Diet on Inflamm-Aging in Childhood Obesity.

Valeria Calcaterra, Elvira Verduci, Chiara Milanta, Marta Agostinelli, Federica Bona, Stefania Croce, Chiara Valsecchi, Maria Antonietta Avanzini, Gianvincenzo Zuccotti

Abstract readReview
In one paragraph

Review in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
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  11. Editorial: Nutrition and neurobehaviors.Frontiers in nutrition · 2025
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Valeria CalcaterraPediatrics and Adolescentology Unit, Department of Internal Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-2137-5974
Elvira VerduciPediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0003-2111-3111
Chiara MilantaPediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Marta AgostinelliPediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Federica BonaPediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.
Stefania CroceImmunology and Transplantation Laboratory, Cell Factory, Pediatric Hematology Oncology, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.
Chiara ValsecchiImmunology and Transplantation Laboratory, Cell Factory, Pediatric Hematology Oncology, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.
Maria Antonietta AvanziniImmunology and Transplantation Laboratory, Cell Factory, Pediatric Hematology Oncology, Fondazione IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0002-6056-9018
Gianvincenzo ZuccottiPediatric Department, Buzzi Children's Hospital, 20154 Milan, Italy.ORCID 0000-0002-2795-9874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Numerous elements of the Mediterranean diet (MD) have antioxidant and anti-inflammatory qualities. (2) Methods: We present a narrative review of the potential benefits of the Mediterranean dietary pattern (MD) in mitigating aging-related inflammation (inflamm-aging) associated with childhood obesity. The mechanisms underlying chronic inflammation in obesity are also discussed. A total of 130 papers were included after screening abstracts and full texts. (3) Results: A complex interplay between obesity, chronic inflammation, and related comorbidities is documented. The MD emerges as a promising dietary pattern for mitigating inflammation. Studies suggest that the MD may contribute to weight control, improved lipid profiles, insulin sensitivity, and endothelial function, thereby reducing the risk of metabolic syndrome in children and adolescents with obesity. (4) Conclusions: While evidence supporting the anti-inflammatory effects of the MD in pediatric obesity is still evolving, the existing literature underscores its potential as a preventive and therapeutic strategy. However, MD adherence remains low among children and adolescents, necessitating targeted interventions to promote healthier dietary habits. Future high-quality intervention studies are necessary to elucidate the specific impact of the MD on inflammation in diverse pediatric populations with obesity and associated comorbidities.

Indexed as

Diet, MediterraneanInflammationPediatric ObesityAdolescentAgingChildHumansMetabolic Syndromechildhood obesitychildreninflamm-agingMediterranean dietnutritionpediatric

Identifiers

PMID38732533
PMCPMC11085692

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.