Evidence map›Paper›PMID 38732346›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Influence of Achalasia on the Spirometry Flow-Volume Curve and Peak Expiratory Flow.

Jelena Jankovic, Branislava Milenkovic, Aleksandar Simic, Ognjan Skrobic, Arschang Valipour, Nenad Ivanovic, Ivana Buha, Jelena Milin-Lazovic, Natasa Djurdjevic, Aleksandar Jandric and 3 more

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Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jelena JankovicClinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0001-8529-8624
Branislava MilenkovicClinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-0767-6869
Aleksandar SimicMedical Faculty, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-4210-580X
Ognjan SkrobicMedical Faculty, University of Belgrade, 11000 Belgrade, Serbia.
Arschang ValipourKarl Landsteiner Institute for Lung Research and Pulmonary Oncology, Klinik Floridsdorf, Vienna Health Care Group, 1210 Vienna, Austria.
Nenad IvanovicClinic for Digestive Surgery, University Clinical Centre of Serbia, 11000 Belgrade, Serbia.
Ivana BuhaClinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Jelena Milin-LazovicMedical Faculty, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-4655-2383
Natasa DjurdjevicClinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-0825-4748
Aleksandar JandricClinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.
Nikola ColicMedical Faculty, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-6516-1970
Stefan StojkovicClinic for Gastroenterohepatology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-2256-7513
Mihailo StjepanovicClinic for Pulmonology, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-1787-1438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAchalasia is an esophageal motor disorder characterized by aperistalsis and the failure of the relaxation of the lower esophageal sphincter. We want to find out whether external compression or recurrent micro-aspiration of undigested food has a functional effect on the airway.

methodsThe aim of this research was to analyze the influence of achalasia on the peak expiratory flow and flow-volume curve. All of the 110 patients performed spirometry.

resultsThe mean diameter of the esophagus was 5.4 ± 2.1 cm, and nine of the patients had mega-esophagus. Seven patients had a plateau in the inspiratory part of the flow-volume curve, which coincides with the patients who had mega-esophagus. The rest of the patients had a plateau in the expiration part of the curve. The existence of a plateau in the diameter of the esophagus of more than 5 cm was significant (

conclusionsAwareness of the influence of achalasia on the pulmonary parameters is important because low values of PEF with a plateau on the spirometry loop can lead to misdiagnosis. The recognition of various patterns of the spirometry loop may help in identifying airway obstruction caused by another non-pulmonary disease such as achalasia.

Indexed as

achalasiaflow–volume curvePEFspirometry

Identifiers

PMID38732346
PMCPMC11083519

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.