Evidence map›Paper›PMID 38732340›Full record

ArticleDiagnostics (Basel, Switzerland)2024

The Contribution of Vessel Wall Magnetic Resonance Imaging to the Diagnosis of Primary and Secondary Central Nervous System Vasculitis.

Serena D'Aniello, Arianna Rustici, Laura Ludovica Gramegna, Claudia Godi, Laura Piccolo, Mauro Gentile, Andrea Zini, Alessandro Carrozzi, Raffaele Lodi, Caterina Tonon and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07448454 (Role of Vessel Wall MRI in Differentiaition Between Intrcranial Atherosclerotic Disease and Vasculitis as Causes of Ischemic Stroke), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07448454 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Role of Vessel Wall MRI in Differentiaition Between Intrcranial Atherosclerotic Disease and Vasculitis as Causes of Ischemic Stroke

TypeinterventionalSponsorAssiut UniversityRan2026 to 2027Enrolled46ConditionsIntracranial Atherosclerotic Disease (ICAD) and VasculitisArmsMRI
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Serena D'AnielloDepartment of Advanced Biomedical Science, University of Napoli "Federico II", 80125 Naples, Italy.
Arianna RusticiDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Laura Ludovica GramegnaVall d'Hebron Research Institute, Vall d'Hebron Barcelona Hospital Campus, 08035 Barcelona, Spain.
Claudia GodiNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Laura PiccoloNeurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.
Mauro GentileNeurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.
Andrea ZiniNeurology and Stroke Center, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.ORCID 0000-0003-1486-4507
Alessandro CarrozziDepartment of Medical and Surgical Sciences (DIMEC), University of Bologna, 40138 Bologna, Italy.ORCID 0009-0006-9576-1284
Raffaele LodiDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.
Caterina TononDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-0506-499X
Massimo Dall'OlioNeuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Bellaria, 40139 Bologna, Italy.
Luigi SimonettiNeuroradiology Unit, IRCCS Istituto delle Scienze Neurologiche di Bologna, Ospedale Maggiore, 40133 Bologna, Italy.
Raffaella ChieffoExperimental Neurophysiology Unit, IRCCS San Raffaele, Institute of Experimental Neurology (INSPE), 20132 Milan, Italy.
Nicoletta AnzaloneNeuroradiology Unit and CERMAC, IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Luigi CirilloDepartment of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, 40138 Bologna, Italy.ORCID 0000-0002-0424-3400

Funding

Associazione Italiana Neuroradiologia (AINR) Prize Young Topic 2023 Neuroradiologia Diagnostica
6 · The paper itself

Abstract

backgroundTo describe high-resolution brain vessel wall MRI (VW-MRI) patterns and morphological brain findings in central nervous system (CNS) vasculitis patients.

methodsFourteen patients with confirmed CNS Vasculitis from two tertiary centers underwent VW-MRI using a 3T scanner. The images were reviewed by two neuroradiologists to assess vessel wall enhancement characteristics and locations.

resultsFourteen patients were included (six females; average age 48 ± 19 years). Diagnoses included primary CNS vasculitis (PCNSV) in six patients and secondary CNS vasculitis (SCNSV) in eight, half of which were infection-related. Thirteen patients showed vessel wall enhancement, which was intense in eleven patients (84.6%) and concentric in twelve (92.3%), affecting the anterior circulation in nine patients (69.2%), posterior in two patients (15.4%), and both circulations in two patients (15.4%). The enhancement patterns were similar across different CNS vasculitis types. DWI changes corresponded with areas of vessel wall enhancement in 77% of patients. Conclusions

Indexed as

cerebral vasculitismagnetic resonanceMRIvessel wallVWI

Identifiers

PMID38732340
PMCPMC11083696

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.