Evidence map›Paper›PMID 38732296›Full record

ArticleDiagnostics (Basel, Switzerland)2024

Differential Diagnosis of Solid Pancreatic Lesions Using Detective Flow Imaging Endoscopic Ultrasonography.

Haruo Miwa, Kazuya Sugimori, Shoichiro Yonei, Hayato Yoshimura, Kazuki Endo, Ritsuko Oishi, Akihiro Funaoka, Hiromi Tsuchiya, Takashi Kaneko, Kazushi Numata and 1 more

Registry-linked trialAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07763561 (Role of Endoscopic Ultrasound-guided Detective Flow Imaging), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07763561 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Role of Endoscopic Ultrasound-guided Detective Flow Imaging (EUS-DFI) for the Evaluation of Solid Pancreatic Tumours: A Prospective, International Multicenter Study

TypeobservationalSponsorJulio Iglesias GarcíaRan2026 to 2027Enrolled48ConditionsPancreatic Neoplasms, Pancreatic Solid Lesions
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Haruo MiwaGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.ORCID 0000-0001-6324-5433
Kazuya SugimoriGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Shoichiro YoneiGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Hayato YoshimuraGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Kazuki EndoGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Ritsuko OishiGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Akihiro FunaokaGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Hiromi TsuchiyaGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Takashi KanekoGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Kazushi NumataGastroenterological Center, Yokohama City University Medical Center, Yokohama 232-0024, Japan.
Shin MaedaDepartment of Gastroenterology, Yokohama City University, Yokohama 236-0004, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The differential diagnosis of solid pancreatic lesions (SPLs) using B-mode endoscopic ultrasonography (EUS) is challenging. Detective flow imaging (DFI) offers the potential for detecting low-flow vessels in the pancreas, thus enhancing diagnostic accuracy. This retrospective study aimed to investigate DFI-EUS findings of SPLs and analyze their differential diagnostic accuracy for pancreatic cancer. We included 104 patients with pathologically confirmed SPLs who underwent EUS between April 2021 and June 2023. Expert endosonographers, blinded to the patients' clinical data, evaluated images obtained through B-mode, eFLOW, and DFI-EUS. The frame rate and vessel detection sensitivity were compared between eFLOW and DFI, and the diagnostic criteria for pancreatic cancer were established. The visualization rate for vessels in SPLs was significantly higher with DFI-EUS (96%) compared to eFLOW (27%). Additionally, DFI showed a superior frame rate, sensitivity (99%), and accuracy (88%) for detecting pancreatic cancer, although with a modest specificity (43%). On DFI-EUS, characteristics such as hypovascularity, peritumoral vessel distribution, or spotty vessel form were suggestive of pancreatic cancer. DFI-EUS significantly improved the visualization of vascular structures within the SPLs, highlighting its efficacy as a diagnostic modality for pancreatic cancer.

Indexed as

detective flow imagingendoscopic ultrasonographypancreatic cancer

Identifiers

PMID38732296
PMCPMC11082975

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.