Evidence map›Paper›PMID 38732202›Full record

ArticleInternational journal of molecular sciences2024

Carnosic Acid Inhibits Herpes Simplex Virus Replication by Suppressing Cellular ATP Synthesis.

Georgina Horváth, Edit Molnár, Zoltán Szabó, Gábor Kecskeméti, László Juhász, Szabolcs Péter Tallósy, József Nyári, Anita Bogdanov, Ferenc Somogyvári, Valéria Endrész and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Georgina HorváthDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.
Edit MolnárRéthy Pál County Hospital, Gyulai Str. 18, 5600 Bekescsaba, Hungary.
Zoltán SzabóDepartment of Medical Chemistry, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Dóm Sq. 8, 6720 Szeged, Hungary.ORCID 0000-0001-8278-8038
Gábor KecskemétiDepartment of Medical Chemistry, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Dóm Sq. 8, 6720 Szeged, Hungary.ORCID 0000-0002-5584-6869
László JuhászInstitute of Surgical Research, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Szőkefalvi-Nagy Béla Str. 6, 6720 Szeged, Hungary.
Szabolcs Péter TallósyInstitute of Surgical Research, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Szőkefalvi-Nagy Béla Str. 6, 6720 Szeged, Hungary.
József NyáriDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.
Anita BogdanovDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.
Ferenc SomogyváriDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.ORCID 0000-0001-8409-892X
Valéria EndrészDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.ORCID 0000-0002-9402-3857
Katalin BuriánDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.ORCID 0000-0003-1300-2374
Dezső P VirokDepartment of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis Str. 6, 6725 Szeged, Hungary.

Funding

European Union EFOP-3.6.2-16-2017-00006University of Szeged Albert Szent-Györgyi Grant
6 · The paper itself

Abstract

Acquiring resistance against antiviral drugs is a significant problem in antimicrobial therapy. In order to identify novel antiviral compounds, the antiviral activity of eight plants indigenous to the southern region of Hungary against herpes simplex virus-2 (HSV-2) was investigated. The plant extracts and the plant compound carnosic acid were tested for their effectiveness on both the extracellular and intracellular forms of HSV-2 on Vero and HeLa cells. HSV-2 replication was measured by a direct quantitative PCR (qPCR). Among the tested plant extracts,

Indexed as

AbietanesAdenosine TriphosphateAntiviral AgentsHerpesvirus 2, HumanPlant ExtractsVirus ReplicationAnimalsChlorocebus aethiopsHeLa CellsHumansVero CellsAbietanesAdenosine TriphosphateAntiviral AgentsPlant Extractssalvinantimicrobialantiviralcarnosic acidcitrate cycleglycolysisherpesherpes simplexmitochondrionoxidative phosphorylationrosemary

Identifiers

PMID38732202
PMCPMC11084413

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.