Evidence map›Paper›PMID 38732102›Full record

ArticleInternational journal of molecular sciences2024

Structure-Function Analysis of the Essential

Tiara Padayachee, David C Lamb, David R Nelson, Khajamohiddin Syed

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Recent Characterization of Key Proteins to Combat Tuberculosis.Advances in experimental medicine and biology · 2026
    Review
  5. Structure-Function Analysis ofInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tiara PadayacheeDepartment of Biochemistry and Microbiology, Faculty of Science, Agriculture and Engineering, University of Zululand, Empangeni 3886, South Africa.ORCID 0000-0001-6667-9982
David C LambFaculty of Medicine, Health and Life Sciences, Swansea University, Swansea SA2 8PP, UK.
David R NelsonDepartment of Microbiology, Immunology and Biochemistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0003-0583-5421
Khajamohiddin SyedDepartment of Biochemistry and Microbiology, Faculty of Science, Agriculture and Engineering, University of Zululand, Empangeni 3886, South Africa.ORCID 0000-0002-1497-3570

Funding

National Research Foundation (NRF), South Africa MND210504599108University of Zululand, South Africa P419
6 · The paper itself

Abstract

Cytochrome P450 CYP121A1 is a well-known drug target against

Indexed as

Cytochrome P-450 Enzyme SystemMycobacterium tuberculosisAntitubercular AgentsBacterial ProteinsCatalytic DomainCrystallography, X-RayCytochrome P-450 Enzyme InhibitorsHumansLigandsModels, MolecularProtein BindingProtein ConformationStructure-Activity RelationshipSubstrate SpecificityAntitubercular AgentsBacterial Proteinscytochrome P-450 CYP121Cytochrome P-450 Enzyme InhibitorsCytochrome P-450 Enzyme SystemLigandsactive siteamino acid residuescrystal structureCYP121A1cytochrome P450cYYhemeMycobacterium tuberculosis

Identifiers

PMID38732102
PMCPMC11084333

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.