Evidence map›Paper›PMID 38732075›Full record

ReviewInternational journal of molecular sciences2024

Melatonin/Sericin Wound Healing Patches: Implications for Melanoma Therapy.

Katarzyna Adamiak, Vivian A Gaida, Jasmin Schäfer, Lina Bosse, Clara Diemer, Russel J Reiter, Andrzej T Slominski, Kerstin Steinbrink, Alina Sionkowska, Konrad Kleszczyński

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Melatonin and the Dental Pulp: A Scoping Review.International endodontic journal · 2026
    Article
  2. Article
  3. Review
  4. Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  5. Review
  6. Review
  7. Review
  8. Biopolymeric Scaffolds with Melatonin for Tissue Engineering-A Review.International journal of molecular sciences · 2025
    Review
  9. Melatonin's Impact on Wound Healing.Antioxidants (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Katarzyna AdamiakDepartment of Biomaterials and Cosmetic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0002-2386-603X
Vivian A GaidaDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0009-0002-7066-4737
Jasmin SchäferDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.
Lina BosseDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.
Clara DiemerDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.
Russel J ReiterDepartment of Cell Systems and Anatomy, Long School of Medicine, UT Health, San Antonio, TX 78229, USA.ORCID 0000-0001-6763-4225
Andrzej T SlominskiDepartment of Dermatology, Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-8963-3995
Kerstin SteinbrinkDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0002-0500-2158
Alina SionkowskaDepartment of Biomaterials and Cosmetic Chemistry, Faculty of Chemistry, Nicolaus Copernicus University, Gagarin 7, 87-100 Toruń, Poland.ORCID 0000-0002-1551-2725
Konrad KleszczyńskiDepartment of Dermatology, University of Münster, Von-Esmarch-Str. 58, 48149 Münster, Germany.ORCID 0000-0002-1311-263X

Funding

Mechanism of action and function of novel secosteroid 20(OH)D3 in the skinR01AR073004 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANDRZEJ T SLOMINSKI · 2018 to 2026
$2.9M
Significance of metabolic activation of lumisterol in the skinR01AR071189 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SLOMINSKI, ANDRZEJ T · 2017 to 2021
$1.6M
BLRD VA I01 BX004293NIAMS NIH HHS R01 AR073004NIH HHS 1R01AR073004-01A1NIH HHS R01AR071189-01A1
6 · The paper itself

Abstract

Melatonin and sericin exhibit antioxidant properties and may be useful in topical wound healing patches by maintaining redox balance, cell integrity, and regulating the inflammatory response. In human skin, melatonin suppresses damage caused by ultraviolet radiation (UVR) which involves numerous mechanisms associated with reactive oxygen species/reactive nitrogen species (ROS/RNS) generation and enhancing apoptosis. Sericin is a protein mainly composed of glycine, serine, aspartic acid, and threonine amino acids removed from the silkworm cocoon (particularly

Indexed as

MelanomaMelatoninSericinsWound HealingAnimalsAntioxidantsHumansSkin NeoplasmsAntioxidantsMelatoninSericinsbiomaterialshydrogelsmelatoninscaffoldssericinskin regenerationwound healing

Identifiers

PMID38732075
PMCPMC11084828

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.