Evidence map›Paper›PMID 38731991›Full record

ArticleInternational journal of molecular sciences2024

Carbonic Anhydrase 2 Deletion Delays the Growth of Kidney Cysts Whereas Foxi1 Deletion Completely Abrogates Cystogenesis in TSC.

Sharon Barone, Kamyar Zahedi, Marybeth Brooks, Manoocher Soleimani

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sharon BaroneResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0001-5710-292X
Kamyar ZahediResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0002-4257-5107
Marybeth BrooksResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0001-6582-2281
Manoocher SoleimaniResearch Services, New Mexico Veterans Health Care System, Albuquerque, NM 87108, USA.ORCID 0000-0003-4909-4469

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
MINORITY INSTITUTIONAL RESEARCH TRAINING PROGRAM (T32)T32HL007736 · NHLBI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI RESTA, THOMAS C · 1993 to 2025
$6.5M
The Role of Intercalated Cells and Their Acid Base and Electrolyte Transport Machinery in Kidney Cystogenesis by Tuberous SclerosisI01BX001000 · VA · CINCINNATI VA MEDICAL CENTER RESEARCH · PI SOLEIMANI, MANOOCHER · 2012 to 2025
–
BLRD VA I01 BX001000NCI NIH HHS P30 CA118100NHLBI NIH HHS T32 HL007736NIH HHS NIH/NHLBIT32HL007736
6 · The paper itself

Abstract

Tuberous sclerosis complex (TSC) presents with renal cysts and benign tumors, which eventually lead to kidney failure. The factors promoting kidney cyst formation in TSC are poorly understood. Inactivation of carbonic anhydrase 2 (

Indexed as

Carbonic Anhydrase IIForkhead Transcription FactorsKidney Diseases, CysticTuberous SclerosisAnimalsGene DeletionKidneyMiceMice, KnockoutTuberous Sclerosis Complex 1 ProteinCarbonic Anhydrase IIForkhead Transcription FactorsFoxi1 protein, mouseTsc1 protein, mouseTuberous Sclerosis Complex 1 ProteinA-intercalated cellscarbonic anhydrase 2cystogenesisFoxi1H+-ATPasemTORC1tuberous sclerosis

Identifiers

PMID38731991
PMCPMC11084925

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.