Evidence map›Paper›PMID 38731967›Full record

ArticleInternational journal of molecular sciences2024

Biosynthetic Pathways of Tryptophan Metabolites in

Hsin-Chieh Kung, Ngoc-Han Bui, Bo-Wun Huang, Nicholas Kiprotich Cheruiyot, Guo-Ping Chang-Chien

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Special Issue "Tryptophan in Nutrition and Health 3.0".International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hsin-Chieh KungInstitute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.
Ngoc-Han BuiInstitute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.
Bo-Wun HuangDepartment of Mechanical and Institute of Mechatronic Engineering, Cheng Shiu University, Kaohsiung 83347, Taiwan.ORCID 0000-0002-6026-5110
Nicholas Kiprotich CheruiyotInstitute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.ORCID 0000-0003-2746-107X
Guo-Ping Chang-ChienInstitute of Environmental Toxin and Emerging Contaminant, Cheng Shiu University, Kaohsiung 83347, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tryptophan metabolites, such as 5-hydroxytryptophan (5-HTP), serotonin, and melatonin, hold significant promise as supplements for managing various mood-related disorders, including depression and insomnia. However, their chemical production via chemical synthesis and phytochemical extraction presents drawbacks, such as the generation of toxic byproducts and low yields. In this study, we explore an alternative approach utilizing

Indexed as

5-HydroxytryptophanBiosynthetic PathwaysSaccharomyces cerevisiaeSerotoninTryptophanChromatography, LiquidMelatoninTandem Mass Spectrometry5-HydroxytryptophanMelatoninSerotoninTryptophan5-hydroxytryptophanindolaminesLC-MS/MSmelatoninprobiotic strainsserotoninsustainabilityyeast strain

Identifiers

PMID38731967
PMCPMC11083699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.