Evidence map›Paper›PMID 38731926›Full record

ArticleInternational journal of molecular sciences2024

Mixed-Lineage Leukaemia Gene Regulates Glucose-Sensitive Gene Expression and Insulin Secretion in Pancreatic Beta Cells.

Satoshi Yoshino, Emi Ishida, Kazuhiko Horiguchi, Shunichi Matsumoto, Yasuyo Nakajima, Atsushi Ozawa, Masanobu Yamada, Eijiro Yamada

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Satoshi YoshinoDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.ORCID 0000-0001-9111-0632
Emi IshidaDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.ORCID 0000-0002-2610-9093
Kazuhiko HoriguchiDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
Shunichi MatsumotoDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.ORCID 0000-0002-3726-9105
Yasuyo NakajimaDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.ORCID 0000-0003-2630-2579
Atsushi OzawaDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.ORCID 0000-0002-3627-2628
Masanobu YamadaDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.
Eijiro YamadaDepartment of Internal Medicine, Division of Endocrinology and Metabolism, Gunma University Graduate School of Medicine, Maebashi 371-8511, Japan.ORCID 0000-0002-0332-8605

Funding

Ministry of Science, Education, Sports and Culture of Japan 18K16191
6 · The paper itself

Abstract

The escalating prevalence of diabetes mellitus underscores the need for a comprehensive understanding of pancreatic beta cell function. Interest in glucose effectiveness has prompted the exploration of novel regulatory factors. The myeloid/lymphoid or mixed-lineage leukaemia gene (

Indexed as

GlucoseGlucose Transporter Type 2Histone-Lysine N-MethyltransferaseInsulin-Secreting CellsInsulin SecretionMyeloid-Lymphoid Leukemia ProteinAnimalsCell LineGene Expression RegulationGlucose Transporter Type 1InsulinMaleMiceMice, KnockoutGlucoseGlucose Transporter Type 1Glucose Transporter Type 2Histone-Lysine N-MethyltransferaseInsulinKmt2a protein, mouseMyeloid-Lymphoid Leukemia ProteinSlc2a1 protein, mouseSlc2a2 protein, mousebeta cellsdiabetesglucose responsivenessinsulinMLLSLC2A1SLC2A2

Identifiers

PMID38731926
PMCPMC11082990

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.