Evidence map›Paper›PMID 38731835›Full record

ArticleInternational journal of molecular sciences2024

Systems Biology for Drug Target Discovery in Acute Myeloid Leukemia.

Svetlana Novikova, Tatiana Tolstova, Leonid Kurbatov, Tatiana Farafonova, Olga Tikhonova, Natalia Soloveva, Alexander Rusanov, Victor Zgoda

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Svetlana NovikovaInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.ORCID 0000-0003-2777-2476
Tatiana TolstovaInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.ORCID 0000-0001-9053-6551
Leonid KurbatovInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.ORCID 0000-0002-8859-0118
Tatiana FarafonovaInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.ORCID 0000-0002-7633-3034
Olga TikhonovaInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
Natalia SolovevaInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.ORCID 0000-0002-8940-1454
Alexander RusanovInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.
Victor ZgodaInstitute of Biomedical Chemistry, Pogodinskaya 10, 119121 Moscow, Russia.ORCID 0000-0002-4532-4274

Funding

Russian Science Foundation 21-74-20122
6 · The paper itself

Abstract

Combining new therapeutics with all-

Indexed as

Leukemia, Myeloid, AcuteSystems BiologyTretinoinAntineoplastic AgentsCell Line, TumorCyclin-Dependent Kinase 6Drug DiscoveryGene Expression ProfilingGene Expression Regulation, LeukemicHL-60 CellsHumansK562 CellsTranscriptomeTumor Necrosis Factor-alphaAntineoplastic AgentsCDK6 protein, humanCyclin-Dependent Kinase 6TretinoinTumor Necrosis Factor-alphaacute myeloid leukemiaall-trans-retinoic acidgranulocytic differentiationHL-60K562NB4proteometranscriptome

Identifiers

PMID38731835
PMCPMC11083274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.