Evidence map›Paper›PMID 38731823›Full record

ArticleInternational journal of molecular sciences2024

Molecularly Imprinted Drug Carrier for Lamotrigine-Design, Synthesis, and Characterization of Physicochemical Parameters.

Monika Sobiech, Sandile M Khamanga, Karol Synoradzki, Tamara J Bednarchuk, Katarzyna Sikora, Piotr Luliński, Joanna Giebułtowicz

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Monika SobiechDepartment of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0002-5687-2874
Sandile M KhamangaFaculty of Pharmacy, Rhodes University, Makhanda 6140, South Africa.ORCID 0000-0003-2374-8460
Karol SynoradzkiInstitute of Molecular Physics, Polish Academy of Sciences, Smoluchowskiego 17, 60-179 Poznań, Poland.ORCID 0000-0002-7732-3284
Tamara J BednarchukInstitute of Low Temperature and Structure Research, Polish Academy of Sciences, Okólna 2, 50-422 Wrocław, Poland.
Katarzyna SikoraDepartment of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Piotr LulińskiDepartment of Organic and Physical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0001-8421-5225
Joanna GiebułtowiczDepartment of Drug Chemistry, Pharmaceutical and Biomedical Analysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0002-2567-4453

Funding

Interdisciplinary Centre for Mathematical and Computational Modelling G68-2Medical University of Warsaw FW24/1/F/MBS/N/21National Research Foundation CSRP200411512596
6 · The paper itself

Abstract

This study presents the initial attempt at introducing a magnetic molecularly imprinted polymer (MIP) designed specifically for lamotrigine with the purpose of functioning as a drug carrier. First, the composition of the magnetic polymer underwent optimization based on bulk polymer adsorption studies and theoretical analyses. The magnetic MIP was synthesized from itaconic acid and ethylene glycol dimethacrylate exhibiting a drug loading capacity of 3.4 ± 0.9 μg g

Indexed as

Drug CarriersLamotrigineMolecularly Imprinted PolymersAdsorptionDrug LiberationHydrogen-Ion ConcentrationMolecular ImprintingSpectroscopy, Fourier Transform InfraredX-Ray DiffractionDrug CarriersLamotrigineMolecularly Imprinted Polymersdrug carrierdrug deliverylamotriginemagnetic particlemolecularly imprinted polymer

Identifiers

PMID38731823
PMCPMC11083086

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.