Evidence map›Paper›PMID 38731532›Full record

ArticleMolecules (Basel, Switzerland)2024

Synthesis of Flavonols and Assessment of Their Biological Activity as Anticancer Agents.

Yu-Hui Hsieh, Pei-Hsuan Hsu, Anren Hu, Yang-Je Cheng, Tzenge-Lien Shih, Jih-Jung Chen

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yu-Hui HsiehBiomedical Industry Ph.D. Program, School of Life Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Pei-Hsuan HsuDepartment of Chemistry, Tamkang University, New Taipei City 251301, Taiwan.
Anren HuDepartment of Laboratory Medicine and Biotechnology, Tzu Chi University, Hualien 970374, Taiwan.
Yang-Je ChengDepartment of Chemistry, Tamkang University, New Taipei City 251301, Taiwan.
Tzenge-Lien ShihDepartment of Chemistry, Tamkang University, New Taipei City 251301, Taiwan.ORCID 0000-0001-5378-0782
Jih-Jung ChenBiomedical Industry Ph.D. Program, School of Life Sciences, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0002-5680-9533

Funding

Ministry of Science and Technology of Taiwan MOST 111-2113-M-032-004National Science and Technology Council of Taiwan NSTC 112-2320-B-A49-028-MY3
6 · The paper itself

Abstract

A series of flavanols were synthesized to assess their biological activity against human non-small cell lung cancer cells (A549). Among the sixteen synthesized compounds, it was observed that compounds

Indexed as

Antineoplastic AgentsApoptosisFlavonolsA549 CellsCaspase 3Cell Line, TumorCell ProliferationDrug Screening Assays, AntitumorFluorouracilHumansLung NeoplasmsMitochondriaMolecular StructureStructure-Activity RelationshipAntineoplastic AgentsCaspase 3FlavonolsFluorouracilanticancer agentflavonolhuman non-small cell lung cancer cell

Identifiers

PMID38731532
PMCPMC11085485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.