Evidence map›Paper›PMID 38731465›Full record

ReviewMolecules (Basel, Switzerland)2024

Pharmacological Activities of

Siu Kan Law, Xiao Xiao Wu, Zhou Jiang, Christy Wing Sum Tong, Wesley Yeuk Lung Chow, Dawn Ching Tung Au

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Identification of the Hypoglycemic Active Components ofMolecules (Basel, Switzerland) · 2024
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Siu Kan LawDepartment of Food and Health Sciences, The Technological and Higher Education Institute of Hong Kong, Tsing Yi, New Territories, Hong Kong, China.ORCID 0000-0002-0454-2048
Xiao Xiao WuLaboratory Medicine Centre, Huazhong University of Science and Technology Union Shenzhen Hospital (Nanshan Hospital), Shenzhen 518056, China.ORCID 0009-0009-8018-552X
Zhou JiangLaboratory Medicine Centre, Huazhong University of Science and Technology Union Shenzhen Hospital (Nanshan Hospital), Shenzhen 518056, China.
Christy Wing Sum TongDepartment of Food and Health Sciences, The Technological and Higher Education Institute of Hong Kong, Tsing Yi, New Territories, Hong Kong, China.ORCID 0009-0002-7171-5313
Wesley Yeuk Lung ChowDepartment of Food and Health Sciences, The Technological and Higher Education Institute of Hong Kong, Tsing Yi, New Territories, Hong Kong, China.ORCID 0000-0002-2226-1485
Dawn Ching Tung AuDepartment of Food and Health Sciences, The Technological and Higher Education Institute of Hong Kong, Tsing Yi, New Territories, Hong Kong, China.ORCID 0000-0002-7622-0064

Funding

Basic and Applied Basic Research Foundation of Guangdong Province (2022A1515111117)Chinese Medicine and Culture Research Center, Research Matching Grant (RMG030a)Nanshan District Health System Major Science and Technology Project (NSZD2023031)
6 · The paper itself

Abstract

Chrysoeriol is an active ingredient derived from the Chinese medicinal herb (CMH) "

methodsNine electronic databases were searched, including WanFang Data, PubMed, Science Direct, Scopus, Web of Science, Springer Link, SciFinder, and China National Knowledge Infrastructure (CNKI), without regard to language constraints. The pharmacological activities of chrysoeriol from

resultsChrysoeriol decreased the mRNA levels of proinflammatory cytokines IL-6, IL-1β, and TNF-α. These were transcriptionally regulated by NF-κB and STAT3 to combat skin inflammation. It also showed promising actions in treating many skin ailments including wound healing, depigmentation, photoprotection, and antiaging.

conclusionThe cutaneous route is the best delivery approach to chrysoeriol across the skin barrier. However, toxicity, dosage, and safety assessments of chrysoeriol in a formulation or nanochrysoeriol on the human epidermis for application in skin diseases must be further investigated.

Indexed as

LoniceraSkin DiseasesAnimalsDrugs, Chinese HerbalFlowersHumansPlant ExtractsDrugs, Chinese Herballonicerae flosPlant Extractschrysoeriolcutaneous routeLonicerae japonicae flospharmacokinetic and pharmacodynamic activitiespharmacological functionskin diseases

Identifiers

PMID38731465
PMCPMC11085288

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.