Evidence map›Paper›PMID 38731398›Full record

ArticleMolecules (Basel, Switzerland)2024

Electropositive Citric Acid-Polyethyleneimine Carbon Dots Carrying the PINK1 Gene Regulate ATP-Related Metabolic Dysfunction in APP/PS1-N2a Cells.

Si Yu, Feng Guo, Yuzhen Luo, Xingfang Zhang, Chenyu Wang, Yiheng Liu, Haiying Zhang

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Si YuKey Laboratory of Brain Science and Health Translational Medicine Research Center in Tropical Environment of Hainan Province, Hainan Medical University, Haikou 571199, China.
Feng GuoKey Laboratory of Brain Science and Health Translational Medicine Research Center in Tropical Environment of Hainan Province, Hainan Medical University, Haikou 571199, China.
Yuzhen LuoKey Laboratory of Brain Science and Health Translational Medicine Research Center in Tropical Environment of Hainan Province, Hainan Medical University, Haikou 571199, China.
Xingfang ZhangKey Laboratory of Brain Science and Health Translational Medicine Research Center in Tropical Environment of Hainan Province, Hainan Medical University, Haikou 571199, China.
Chenyu WangClinical Medical College, Gannan Medical University, Ganzhou 341000, China.
Yiheng LiuAffiliated Haikou Hospital of Xiangya Medical College, Central South University, Haikou 571199, China.
Haiying ZhangHainan Provincial Key Laboratory of Carcinogenesis and Intervention, Hainan Medical University, Haikou 571199, China.ORCID 0009-0008-7126-1781

Funding

Hainan Province Science and Technology Special Fund of China ZDYF2022SHFZ290Hainan Provincial Natural Science Foundation of China 821RC562Innovative Research Projects for Graduate Students in Hainan Province, China Qhys2022-296National Natural Science Foundation of China 81660224
6 · The paper itself

Abstract

(1) Background: Alzheimer's disease (AD) is characterized by β-amyloid (Aβ) peptide accumulation and mitochondrial dysfunction during the early stage of disease. PINK1 regulates the balance between mitochondrial homeostasis and bioenergy supply and demand via the PINK1/Parkin pathway, Na

Indexed as

Adenosine TriphosphateCarbonCitric AcidPolyethyleneimineProtein KinasesQuantum DotsAlzheimer DiseaseAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsCell LineHumansMembrane Potential, MitochondrialMiceMitochondriaPTEN-Induced Putative KinaseAdenosine TriphosphateAmyloid beta-PeptidesAmyloid beta-Protein PrecursorCarbonCitric AcidPolyethyleneimineProtein KinasesPTEN-Induced Putative KinaseReactive Oxygen SpeciesAlzheimer’s diseaseATP-related metabolomicselectron transport chainPINK1 gene

Identifiers

PMID38731398
PMCPMC11085363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.