Evidence map›Paper›PMID 38730863›Full record

ArticleMaterials (Basel, Switzerland)2024

Exploring the Potential of a Novel Iodine-Based Material as an Alternative Contrast Agent in X-ray Imaging Studies.

Kristina Bliznakova, Iliyan Kolev, Nikolay Dukov, Tanya Dimova, Zhivko Bliznakov

Abstract read
In one paragraph

Article in Materials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristina BliznakovaDepartment of Medical Equipment Electronic and Information Technologies in Healthcare, Faculty of Public Health, Medical University of Varna, 9002 Varna, Bulgaria.
Iliyan KolevDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Varna, 9002 Varna, Bulgaria.
Nikolay DukovDepartment of Medical Equipment Electronic and Information Technologies in Healthcare, Faculty of Public Health, Medical University of Varna, 9002 Varna, Bulgaria.ORCID 0000-0003-2697-6194
Tanya DimovaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Varna, 9002 Varna, Bulgaria.
Zhivko BliznakovDepartment of Medical Equipment Electronic and Information Technologies in Healthcare, Faculty of Public Health, Medical University of Varna, 9002 Varna, Bulgaria.

Funding

European Union - NextGenerationEU BG-RRP-2.004-0009-C02
6 · The paper itself

Abstract

backgroundContrast-enhanced mammography is one of the new emerging imaging techniques used for detecting breast tissue lesions. Optimization of imaging protocols and reconstruction techniques for this modality, however, requires the involvement of physical phantoms. Their development is related to the use of radiocontrast agents. This study assesses the X-ray properties of a novel contrast material in clinical settings. This material is intended for experimental use with physical phantoms, offering an alternative to commonly available radiocontrast agents. MATERIALS AND

methodsThe water-soluble sodium salt of the newly synthesized diiodine-substituted natural eudesmic acid, Sodium 2,6-DiIodo-3,4,5-TriMethoxyBenzoate [NaDITMB], has been investigated with respect to one of the most commonly applied radiocontrast medium in medical practice-Omnipaque RESULTS AND DISCUSSION: Simulation results revealed equivalent absorptions between the two simulated radiocontrast agents. Experimental findings supported these simulations, showing a maximum deviation of 3.7% between the image gray values of contrast materials for NaDITMB and Omnipaque solutions for a 46 kVp X-ray beam. Higher kVp X-ray beams show even smaller deviations in the mean grey values of the imaged contrast agents, with the NaDITMB solution demonstrating less than a 2% deviation compared to Omnipaque.

conclusionThe proposed contrast agent is a suitable candidate for use in experimental work related to contrast-enhanced imaging by utilizing phantoms. It boasts the advantages of easy synthesis and is recognized for its safety, ensuring a secure environment for both the experimenter and the environment.

Indexed as

physical phantomsradiocontrast agentsimulationsX-ray imaging

Identifiers

PMID38730863
PMCPMC11084318

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.