Evidence map›Paper›PMID 38730671›Full record

ArticleCancers2024

Direct Implantation of Patient Brain Tumor Cells into Matching Locations in Mouse Brains for Patient-Derived Orthotopic Xenograft Model Development.

Lin Qi, Patricia Baxter, Mari Kogiso, Huiyuan Zhang, Frank K Braun, Holly Lindsay, Sibo Zhao, Sophie Xiao, Aalaa Sanad Abdallah, Milagros Suarez and 12 more

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Medulloblastoma: biology and immunotherapy.Frontiers in immunology · 2025
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Lin QiShenzhen Key Laboratory for Systems Medicine in Inflammatory Diseases, School of Medicine, Sun Yat-sen University, Shenzhen 510080, China.ORCID 0000-0003-2491-2701
Patricia BaxterTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Mari KogisoTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Huiyuan ZhangTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Frank K BraunTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-5514-1412
Holly LindsayTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Sibo ZhaoTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0009-0003-6401-7186
Sophie XiaoAnn & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Aalaa Sanad AbdallahAnn & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.ORCID 0000-0001-9064-5846
Milagros SuarezAnn & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Zilu HuangAnn & Robert H. Lurie Children's Hospital of Chicago, Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.
Wan Yee TeoTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-1046-1674
Litian YuTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Xiumei ZhaoTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Zhigang LiuTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-4043-3196
Yulun HuangTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Jack M SuTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Tsz-Kwong ManTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Ching C LauTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Laszlo PerlakyTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Yuchen DuTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
Xiao-Nan LiTexas Children's Cancer Center, Texas Children's Hospital, Baylor College of Medicine, Houston, TX 77030, USA.

Funding

Patient-derived orthotopic xenograft models for cancer disparity studies of pediatric brain tumorsU01CA199288 · NCI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI Xiaonan Li · 2015 to 2026
$6.8M
Matching panels of in vivo and in vitro model system of pediatric brain tumorsU01CA217613 · NCI · LURIE CHILDREN'S HOSPITAL OF CHICAGO · PI LI, XIAONAN · 2020 to 2024
$2.9M
(PQD-5) Patient derived orthotopic xenograft models for drug response predictionR01CA185402 · NCI · BAYLOR COLLEGE OF MEDICINE · PI LI, XIAONAN · 2014 to 2017
$1.3M
NCI NIH HHS R01 CA185402NCI NIH HHS U01 CA199288NCI NIH HHS U01 CA217613NIH HHS 1U01CA199288NIH HHS 2UO1 CA199288-06NIH HHS CA185402NIH HHS UO1 1-U01-CA217613-01A1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

brain tumorcancerorthotopic xenograft model

Identifiers

PMID38730671
PMCPMC11083000

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.