Evidence map›Paper›PMID 38730595›Full record

ReviewCancers2024

Prostate-Specific Membrane Antigen-Targeted Therapy in Prostate Cancer: History, Combination Therapies, Trials, and Future Perspective.

Francesco Mattana, Lorenzo Muraglia, Antonio Barone, Marzia Colandrea, Yasmina Saker Diffalah, Silvia Provera, Alfio Severino Cascio, Emanuela Omodeo Salè, Francesco Ceci

Abstract readReview
In one paragraph

Review in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. [The Prostate · 2026
    Observational
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Preclinical Evaluation of Biodistribution and Toxicity of [International journal of molecular sciences · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Francesco MattanaDivision of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-9523-7315
Lorenzo MuragliaDivision of Nuclear Medicine, Humanitas IRCCS, 20141 Milan, Italy.ORCID 0000-0002-8508-8368
Antonio BaroneDivision of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Marzia ColandreaDivision of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-6684-2938
Yasmina Saker DiffalahDivision of Nuclear Medicine, Hospital Clínico Universitario Lozano Blesa, 50009 Zaragoza, Spain.
Silvia ProveraDivision of Pharmacy, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Alfio Severino CascioDivision of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Emanuela Omodeo SalèDivision of Pharmacy, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.
Francesco CeciDivision of Nuclear Medicine, IEO European Institute of Oncology IRCCS, 20141 Milan, Italy.ORCID 0000-0001-9785-5248

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the last decades, the development of PET/CT radiopharmaceuticals, targeting the Prostate-Specific Membrane Antigen (PSMA), changed the management of prostate cancer (PCa) patients thanks to its higher diagnostic accuracy in comparison with conventional imaging both in staging and in recurrence. Alongside molecular imaging, PSMA was studied as a therapeutic agent targeted with various isotopes. In 2021, results from the VISION trial led to the Food and Drug Administration (FDA) approval of [

Indexed as

lutetiumoncologyprostate cancerPSMAradioligand therapytargeted therapy

Identifiers

PMID38730595
PMCPMC11083597

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.