Evidence map›Paper›PMID 38730594›Full record

ArticleCancers2024

Assessing the Effects of Curcumin and 450 nm Photodynamic Therapy on Oxidative Metabolism and Cell Cycle in Head and Neck Squamous Cell Carcinoma: An In Vitro Study.

Silvia Ravera, Claudio Pasquale, Isabella Panfoli, Matteo Bozzo, Dimitrios Agas, Silvia Bruno, Michael R Hamblin, Andrea Amaroli

Abstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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  7. 457 nm LED blue light inhibits oral squamous cell carcinoma cell proliferation via the PI3K/AKT pathway and autophagy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Silvia RaveraDepartment of Experimental Medicine (DIMES), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-0803-1042
Claudio PasqualeDepartment of Surgical and Diagnostic Sciences (DISC), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0003-4747-6471
Isabella PanfoliDepartment of Pharmacy (DIFAR), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-6261-1128
Matteo BozzoBIO-Photonics Overarching Research Laboratory (BIOPHOR), Department of Earth, Environmental and Life Sciences (DISTAV), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-7452-3758
Dimitrios AgasSchool of Biosciences and Veterinary Medicine, University of Camerino, 62032 Camerino, Italy.
Silvia BrunoDepartment of Experimental Medicine (DIMES), University of Genoa, 16132 Genoa, Italy.
Michael R HamblinLaser Research Centre, Faculty of Health Science, University of Johannesburg, Johannesburg 2092, South Africa.ORCID 0000-0001-6431-4605
Andrea AmaroliBIO-Photonics Overarching Research Laboratory (BIOPHOR), Department of Earth, Environmental and Life Sciences (DISTAV), University of Genoa, 16132 Genoa, Italy.ORCID 0000-0002-0494-7942

Funding

Fondo per la Ricerca di Ateneo (FRA) University of Genoa 100022-2023-AA-FRA_001Italian Association for Cancer Research MFAG-25850
6 · The paper itself

Abstract

Oral cancer is the 16th most common malignant tumor worldwide. The risk of recurrence and mortality is high, and the survival rate is low over the following five years. Recent studies have shown that curcumin causes apoptosis in tumor cells by affecting F

Indexed as

antioxidant enzymes activitycellular growthenergy metabolismhead and neck squamous cell carcinoma (HNSCC)human primary fibroblastsintracellular malondialdehyde concentrationoxidative phosphorylation (OxPhos) activityoxidative stressphotochemotherapyviability

Identifiers

PMID38730594
PMCPMC11083672

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.