Evidence map›Paper›PMID 38730168›Full record

ArticleBritish dental journal2024

Prevention of infective endocarditis in at-risk patients: how should dentists proceed in 2024?

Martin Thornhill, Bernard Prendergast, Mark Dayer, Ash Frisby, Peter Lockhart, Larry M Baddour

Abstract read
In one paragraph

Article in British dental journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Martin ThornhillProfessor of Translational Research in Dentistry, Unit of Oral and Maxillofacial Medicine, Surgery and Pathology, School of Clinical Dentistry, University of Sheffield, Sheffield, UK. M.Thornhill@Sheffield.ac.uk.
Bernard PrendergastProfessor of Cardiology, Guy´s and St Thomas´ Hospital, London and Chair of Cardiology, Cleveland Clinic, London, UK.
Mark DayerProfessor and Consultant Cardiologist, Cardiovascular Research Institute, Mater Private Network, Dublin, Ireland.
Ash FrisbyPatient Advocate, London, UK.
Peter LockhartResearch Professor, Department of Oral Medicine/Oral and Maxillofacial Surgery, Atrium Health´s Carolinas Medical Centre, Charlotte, North Carolina, USA; Adjunct Professor, Department of Otolaryngology, Wake Forest University School of Medicine, North Carolina, USA.
Larry M BaddourProfessor Emeritus, Division of Public Health, Infectious Diseases and Occupational Health, Departments of Medicine and Cardiovascular Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

National Institute for Health and Care Excellence (NICE) guidelines are ambiguous over the need for patients at increased risk of infective endocarditis (IE) to receive antibiotic prophylaxis (AP) prior to invasive dental procedures (IDPs), and this has caused confusion for patients and dentists alike. Moreover, the current law on consent requires clinicians to ensure that patients are made aware of any material risk they might be exposed to by any proposed dental treatment and what can be done to ameliorate this risk, so that the patient can decide for themselves how they wish to proceed. The aim of this article is to provide dentists with the latest information on the IE-risk posed by IDPs to different patient populations (the general population and those defined as being at moderate or high risk of IE), and data on the effectiveness of AP in reducing the IE risk in these populations. This provides the information dentists need to facilitate the informed consent discussions they are legally required to have with patients at increased risk of IE about the risks posed by IDPs and how this can be minimised. The article also provides practical information and advice for dentists on how to manage patients at increased IE risk who present for dental treatment.

Indexed as

Antibiotic ProphylaxisEndocarditisDental CareDentistsEndocarditis, BacterialHumansInformed ConsentRisk Factors

Identifiers

PMID38730168
PMCPMC11087238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.