Evidence map›Paper›PMID 38730079›Full record

SynthesisScientific reports2024

Early nutrition is safe and does not increase complications after upper gastrointestinal bleeding-a systematic review and meta-analysis of randomized controlled trials.

Mahmoud Obeidat, Brigitta Teutsch, Diana-Elena Floria, Dániel Sándor Veres, Péter Hegyi, Bálint Erőss

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mahmoud ObeidatCentre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary.
Brigitta TeutschCentre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary.
Diana-Elena FloriaCentre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary.
Dániel Sándor VeresCentre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary.
Péter HegyiCentre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary.
Bálint ErőssCentre for Translational Medicine, Semmelweis University, Budapest, 1085, Hungary. dr.eross.balint@gmail.com.

Funding

Innovációs és Technológiai Minisztérium ÚNKP-22-3-I-PTE-1693
6 · The paper itself

Abstract

Despite a lack of evidence, patients are often not fed for 48-96 h after upper gastrointestinal bleeding (UGIB); however, many trials have demonstrated the benefits of early nutrition (EN). We conducted a meta-analysis of randomized controlled trials (RTCs) to evaluate the outcomes of EN compared to delayed nutrition (DN) after UGIB. The protocol was registered on PROSPERO (CRD42022372306). PubMed, Embase, CENTRAL, Scopus, and Web of Science were searched on the 27th of April 2024 to identify eligible RCTs. The primary outcomes were early (within 7 days) and late (within 30-42 days) mortality and rebleeding. Pooled risk ratios (RR), mean differences (MD), and corresponding 95% confidence intervals (CI) were calculated using a random-effects model. A total of 10 trials with 1051 patients were included in the analysis. Early mortality was not significantly different between the two groups (RR 1.20, CI 0.85-1.71, I

Indexed as

Gastrointestinal HemorrhageRandomized Controlled Trials as TopicHumansLength of StayTreatment Outcome

Identifiers

PMID38730079
PMCPMC11087503

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.