Evidence map›Paper›PMID 38730063›Full record

ArticleScientific reports2024

Maximally informative feature selection using Information Imbalance: Application to COVID-19 severity prediction.

Romina Wild, Emanuela Sozio, Riccardo G Margiotta, Fabiana Dellai, Angela Acquasanta, Fabio Del Ben, Carlo Tascini, Francesco Curcio, Alessandro Laio

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Romina WildInternational School for Advanced Studies (SISSA), Via Bonomea 265, 34136, Trieste, Italy.
Emanuela SozioInfectious Disease Unit, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Via Pozzuolo 330, 33100, Udine, Italy.
Riccardo G MargiottaInternational School for Advanced Studies (SISSA), Via Bonomea 265, 34136, Trieste, Italy.
Fabiana DellaiInfectious Disease Unit, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Via Pozzuolo 330, 33100, Udine, Italy.
Angela AcquasantaInfectious Disease Unit, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Via Pozzuolo 330, 33100, Udine, Italy.
Fabio Del BenDepartment of Medicine (DAME), University of Udine, Via Palladio 8, 33100, Udine, Italy.
Carlo TasciniInfectious Disease Unit, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Via Pozzuolo 330, 33100, Udine, Italy.
Francesco CurcioInfectious Disease Unit, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Via Pozzuolo 330, 33100, Udine, Italy.
Alessandro LaioInternational School for Advanced Studies (SISSA), Via Bonomea 265, 34136, Trieste, Italy. laio@sissa.it.

Funding

Horizon 2020 Framework Programme 824143
6 · The paper itself

Abstract

Clinical databases typically include, for each patient, many heterogeneous features, for example blood exams, the clinical history before the onset of the disease, the evolution of the symptoms, the results of imaging exams, and many others. We here propose to exploit a recently developed statistical approach, the Information Imbalance, to compare different subsets of patient features and automatically select the set of features that is maximally informative for a given clinical purpose, especially in minority classes. We adapt the Information Imbalance approach to work in a clinical framework, where patient features are often categorical and are generally available only for a fraction of the patients. We apply this algorithm to a data set of

Indexed as

AlgorithmsCOVID-19SARS-CoV-2Severity of Illness IndexDatabases, FactualFemaleHumansMale

Identifiers

PMID38730063
PMCPMC11087653

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.