Evidence map›Paper›PMID 38729628›Full record

ArticleBritish journal of sports medicine2024

Baseline clinical and MRI risk factors for hamstring reinjury showing the value of performing baseline MRI and delaying return to play: a multicentre, prospective cohort of 330 acute hamstring injuries.

Muhammad Ikhwan Zein, Milo J K Mokkenstorm, Marco Cardinale, Louis Holtzhausen, Rod Whiteley, Maarten H Moen, Guus Reurink, Johannes L Tol, Qatari and Dutch Hamstring Study Group

2 registry-linked trialsAbstract readMulticenter Study
In one paragraph

Article in British journal of sports medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01812564 phase2completednot on this map

Clinical Utilization of Growth Factors Preparations in the Management of Acute Hamstring Muscle Strain Injury

TypeinterventionalSponsorAspetarRan2009 to 2014Enrolled90ConditionsAcute Hamstring Muscle Strain InjuryArmsPlatelet Poor Plasma (PPP), Platelet Rich Plasma (PRP)
NCT02104258 nacompletednot on this map

Rehabilitation of Acute Hamstring Injuries in Male Athletes: A Prospective Single-site Randomized Controlled Clinical Trial Comparing Two Rehabilitation Protocols With Different Emphasis on Eccentric Exercises

TypeinterventionalSponsorAspetarRan2014 to 2020Enrolled90ConditionsStrainsArmsPhysiotherapy ASPETAR, Physiotherapy ASPETAR+
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muhammad Ikhwan ZeinDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC Location AMC, Amsterdam, The Netherlands m.i.zein@amsterdamumc.nl.ORCID http://orcid.org/0000-0003-3728-5065
Milo J K MokkenstormDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.
Marco CardinaleSports Science, Aspetar Orthopaedic and Sports Medicine Hospital, Doha, Ad Dawhah, Qatar.ORCID http://orcid.org/0000-0002-2777-8707
Louis HoltzhausenSports Medicine Department, Aspetar Qatar Orthopaedic and Sports Medicine Hospital, Doha, Qatar.ORCID http://orcid.org/0000-0002-4002-8679
Rod WhiteleyAspetar Orthopaedic and Sports Medicine Hospital, Doha, Ad Dawhah, Qatar.ORCID http://orcid.org/0000-0002-1452-6228
Maarten H MoenDepartment of Sports Medicine, Bergman Clinics BV, Naarden, The Netherlands.ORCID http://orcid.org/0000-0002-3840-7928
Guus ReurinkDepartment of Orthopedic Surgery and Sports Medicine, Amsterdam UMC Location AMC, Amsterdam, The Netherlands.ORCID http://orcid.org/0000-0002-4299-7780
Johannes L TolAspetar Orthopaedic and Sports Medicine Hospital, Doha, Ad Dawhah, Qatar.
Qatari and Dutch Hamstring Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesStudies identifying clinical and MRI reinjury risk factors are limited by relatively small sample sizes. This study aimed to examine the association between baseline clinical and MRI findings with the incidence of hamstring reinjuries using a large multicentre dataset.

methodsWe merged data from four prospective studies (three randomised controlled trials and one ongoing prospective case series) from Qatar and the Netherlands. Inclusion criteria included patients with MRI-confirmed acute hamstring injuries (<7 days). We performed multivariable modified Poisson regression analysis to assess the association of baseline clinical and MRI data with hamstring reinjury incidence within 2 months and 12 months of follow-up.

results330 and 308 patients were included in 2 months (31 (9%) reinjuries) and 12 months (52 (17%) reinjuries) analyses, respectively. In the 2-month analysis, the presence of discomfort during the active knee extension test was associated with reinjury risk (adjusted risk ratio (ARR) 3.38; 95% CI 1.19 to 9.64). In the 12 months analysis, the time to return to play (RTP) (ARR 0.99; 95% CI 0.97 to 1.00), straight leg raise angle on the injured leg (ARR 0.98; 95% CI 0.96 to 1.00), the presence of discomfort during active knee extension test (ARR 2.52; 95% CI 1.10 to 5.78), the extent of oedema anteroposterior on MRI (ARR 0.74; 95% CI 0.57 to 0.96) and myotendinous junction (MTJ) involvement on MRI (ARR 3.10; 95% CI 1.39 to 6.93) were independently associated with hamstring reinjury.

conclusionsTwo clinical findings (the presence of discomfort during active knee extension test, lower straight leg raise angle on the injured leg), two MRI findings (less anteroposterior oedema, MTJ involvement) and shorter time to RTP were independently associated with increased hamstring reinjury risk. These findings may assist the clinician to identify patients at increased reinjury risk following acute hamstring injury. TRIAL REGISTRATION NUMBERS: NCT01812564; NCT02104258; NL2643; NL55671.018.16.

Indexed as

Athletic InjuriesHamstring MusclesMagnetic Resonance ImagingReinjuriesReturn to SportAdolescentAdultFemaleHumansMaleNetherlandsProspective StudiesQatarRisk FactorsYoung AdultHamstring MusclesRecurrenceRisk factorSporting injuriesSports medicine

Identifiers

PMID38729628
PMCPMC11228232

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.