Evidence map›Paper›PMID 38729155›Full record

ReviewStem cell reports2024

Retinal transplant immunology and advancements.

Victor L Perez, Hazem M Mousa, Kiyoharu J Miyagishima, Amberlynn A Reed, An-Jey A Su, Thomas N Greenwell, Kia M Washington

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Stem cell reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Monitoring Gene Expression in Retina with synthetic serum markers.bioRxiv : the preprint server for biology · 2026
    Article
  4. Review
  5. Review
  6. The neuroimmune interface in retinal regeneration.Progress in retinal and eye research · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Victor L PerezDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA; Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA. Electronic address: vperez4@miami.edu.
Hazem M MousaDepartment of Ophthalmology, Duke University Medical Center, Durham, NC, USA.
Kiyoharu J MiyagishimaRetinal Neurophysiology Section, National Eye Institute, NIH, Bethesda, MD, USA.
Amberlynn A ReedNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
An-Jey A SuDepartment of Surgery, University of Colorado School of Medicine, CU Anschutz Medical Campus, Aurora, CO 80045, USA.
Thomas N GreenwellNational Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Kia M WashingtonDepartment of Surgery, University of Colorado School of Medicine, CU Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address: kia.washington@cuanschutz.edu.

Funding

Local regulation and deletion of T cells to induce tolerance and establish long-term survival of high-risk corneal transplantsR01EY030283 · NEI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Robert Benjamin Levy, Victor L Perez · 2020 to 2026
$3.1M
Aging and Metacognition in Strategic Skill AcquisitionR01AG024485 · NIA · GEORGIA INSTITUTE OF TECHNOLOGY · PI HERTZOG, CHRISTOPHER K · 2004 to 2008
$1.3M
NEI NIH HHS R01 EY030283NIA NIH HHS R01 AG024485
6 · The paper itself

Abstract

Several gaps and barriers remain for transplanting stem cells into the eye to treat ocular disease, especially diseases of the retina. While the eye has historically been considered immune privileged, recent thinking has identified the immune system as both a barrier and an opportunity for eye stem cell transplantation. Recent approaches leveraging scaffolds or cloaking have been considered in other tissues beyond immune suppression. This perspective paper outlines approaches for transplantation and proposes opportunities to overcome barriers of the immune system in stem cell transplantation in the eye.

Indexed as

RetinaStem Cell TransplantationAnimalsHumansRetinal DiseasesTransplantation Immunology

Identifiers

PMID38729155
PMCPMC11297553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.