Evidence map›Paper›PMID 38728004›Full record

ArticleUpdates in surgery2024

Conditional survival nomogram for patients with colon mucinous adenocarcinoma to predict prognosis: a dynamic survival analysis.

Huajun Cai, Ye Wang, Shoufeng Li, Zhen Pan, Tianbao Xu, Yunjin Wang, Yiyi Zhang, Jinfu Zhuang, Xing Liu, Guoxian Guan

Abstract read
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In one paragraph

Article in Updates in surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The Power of MUC2 in Mucinous Adenocarcinomas.Pathobiology : journal of immunopathology, molecular and cellular biology · 2026
    Review
  2. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Huajun Cai *Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Ye Wang *Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Shoufeng Li *Department of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Zhen PanDepartment of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Tianbao XuDepartment of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Yunjin WangDepartment of Pediatric Surgery, Fujian Maternity and Child Health Hospital, Affiliated Hospital of Fujian Medical University, Fuzhou, China.
Yiyi ZhangDepartment of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Jinfu ZhuangDepartment of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Xing LiuDepartment of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Guoxian GuanDepartment of Colorectal Surgery, The First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China. fjxhggx@163.com.

Funding

Joint Funds for the Innovation of Science and Technology, Fujian Province No. 2020Y9125National Natural Science Foundation of China No. 82172800Talent programs granted from The First Affiliated Hospital of Fujian Medical University YJRC3600
6 · The paper itself

Abstract

The aim was to assess conditional survival for colon mucinous adenocarcinoma (MAC) patients, and to construct nomograms to predict conditional survival probability. Survival analysis was done using conditional survival, which was defined as the probability of surviving additional y years for patients who have survived for x years. The mathematical definition was express as: CS (y|x) = S (x + y)/S (x). Cox regression analyses were used to identify prognostic factors. A nomogram is constructed to predict conditional disease-free survival (DFS) and overall survival (OS) probability according to years that already survive. A total of 179 colon MAC patients were included. The 5-year DFS was 67% after surgery, and the 5-year survival probability of patients, who already survived 1, 2, 3, and 4 years were 75%, 87%, 95%, and 98%, respectively. The 5-year OS was 73% after surgery and increased to 76%, 82%, 88%, and 92% at 1, 2, 3, and 4 years, respectively. Subgroup analyses demonstrated the superiority of conditional survival was more pronounced in advanced stages than in stage I. And pT stage, pN stage, and lymphovascular invasion were significantly associated with DFS and OS. Conditional survival nomograms were constructed to predict the 5-year conditional DFS and OS probability given survival for 1, 2, 3, 4 years after surgery. Conditional survival can provide dynamic survival probability according to years that already survive, especially for patients with advanced stages. Taking into account the years already survived accounted for, novel nomograms contributed to effectively predicting conditional survival.

Indexed as

Adenocarcinoma, MucinousColonic NeoplasmsNomogramsAdultAgedAged, 80 and overDisease-Free SurvivalFemaleHumansMaleMiddle AgedNeoplasm StagingPrognosisRetrospective StudiesSurvival AnalysisSurvival RateColon mucinous adenocarcinomaConditional survivalNomogramPrognosisSurvival probability

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.