ArticleCNS neuroscience & therapeutics2024
Outcomes and risk factors for infection after endovascular treatment in patients with acute ischemic stroke.
Article in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Hirudin as a Therapeutic and Brain-Delivery Platform: From Stroke to Central Nervous System Disorders.International journal of molecular sciences · 2026Review
- Clinical application of the HALP score for predicting early neurological deterioration in older patients with acute cerebral infarction.Biomedical reports · 2026Article
- Predicting stroke-associated pneumonia for acute ischemic stroke patients post intravenous thrombolysis: the post-IVT-SAP risk score.Frontiers in medicine · 2026Article
- Association between neutrophil to high-density lipoprotein ratio and futile recanalization in patients with acute ischemic stroke.Neurosurgical review · 2025Article
- Endovascular Treatment of Stroke and Anesthesia Technique: What Is the Best Approach, According to the Literature?Neurology international · 2025Review
- MgSOTheranostics · 2025Article
- Predicting 28-day mortality for patients with acute anterior circulation large vessel occlusion stroke following endovascular treatment in neurology intensive care units.Frontiers in neurology · 2025Article
- Predictive value of cerebrospinal fluid heparin-binding protein and CD64 expression for postoperative central nervous system infection following intracerebral hemorrhage surgery.American journal of translational research · 2025Article
- Risk Factors and Prognosis Analyses of Hospital-Acquired Pneumonia in Elderly Critically Ill Patients with Acute Ischemic Stroke Based on Machine Learning.Infection and drug resistance · 2025Article
- Outcomes and risk factors for infection after endovascular treatment in patients with acute ischemic stroke.CNS neuroscience & therapeutics · 2024Article
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Authors and funding
7 authors.
Funding
Abstract
aimsInfection is a common complication following acute ischemic stroke (AIS) and significantly contributes to poor functional outcomes after stroke. This study aimed to investigate the effects of infection after endovascular treatment (post-EVT infection) on clinical outcomes and risk factors in patients with AIS.
methodsWe retrospectively analyzed AIS patients treated with endovascular treatment (EVT) between January 2016 and December 2022. A post-EVT infection was defined as any infection diagnosed within 7 days after EVT. The primary outcome was functional independence, defined as a modified Rankin scale (mRS) score of 0-2 at 90 days. A multivariable logistic regression analysis was conducted to determine independent predictors of post-EVT infection and the associations between post-EVT infection and clinical outcomes.
resultsA total of 675 patients were included in the analysis; 306 (45.3%) of them had post-EVT infections. Patients with post-EVT infection had a lower rate of functional independence than patients without infection (31% vs 65%, p = 0.006). In addition, patients with post-EVT infection achieved less early neurological improvement (ENI) after EVT (25.8% vs 47.4%, p < 0.001). For safety outcomes, the infection group had a higher incidence of any intracranial hemorrhage (23.9% vs 15.7%, p = 0.01) and symptomatic intracranial hemorrhage (10.1% vs 5.1%, p = 0.01). Unsuccessful recanalization (aOR 1.87, 95% CI 1.11-3.13; p = 0.02) and general anesthesia (aOR 2.22, 95% CI 1.25-3.95; p = 0.01) were identified as independent predictors for post-EVT infection in logistic regression analysis.
conclusionAIS patients who develop post-EVT infections are more likely to experience poor clinical outcomes. Unsuccessful recanalization and general anesthesia were independent risk factors for the development of post-EVT infection.
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