Evidence map›Paper›PMID 38727401›Full record

ArticleNanomaterials (Basel, Switzerland)2024

Assessment of Ingested Micro- and Nanoplastic (MNP)-Mediated Genotoxicity in an In Vitro Model of the Small Intestinal Epithelium (SIE).

Zhenning Yang, Glen M DeLoid, Joshua Baw, Helmut Zarbl, Philip Demokritou

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Application of the Comet Assay in Advanced In Vitro Models.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Hydrophobins fromEnvironmental science & technology · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zhenning YangNanoscience and Advanced Materials Center, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854, USA.ORCID 0000-0003-0989-5544
Glen M DeLoidNanoscience and Advanced Materials Center, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854, USA.
Joshua BawErnest Mario School of Pharmacy, Rutgers University, Piscataway, NJ 08854, USA.
Helmut ZarblEnvironmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854, USA.
Philip DemokritouNanoscience and Advanced Materials Center, Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ 08854, USA.ORCID 0000-0002-2484-9143

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI PANOS G. GEORGOPOULOS · 1988 to 2026
$47.4M
NIEHS NIH HHS P30 ES005022
6 · The paper itself

Abstract

Micro- and nanoplastics (MNPs) have become ubiquitous contaminants of water and foods, resulting in high levels of human ingestion exposure. MNPs have been found in human blood and multiple tissues, suggesting that they are readily absorbed by the gastrointestinal tract (GIT) and widely distributed. Growing toxicological evidence suggests that ingested MNPs may pose a serious health threat. The potential genotoxicity of MNPs, however, remains largely unknown. In this study, genotoxicity of primary and environmentally relevant secondary MNPs was assessed in a triculture small intestinal epithelium (SIE) model using the CometChip assay. Aqueous suspensions of 25 and 1000 nm carboxylated polystyrene spheres (PS25C and PS1KC), and incinerated polyethylene (PEI PM

Indexed as

genotoxicityingestionmicro- and nanoplastics (MNPs)polyethylene (PE)polystyrene (PS)

Identifiers

PMID38727401
PMCPMC11085749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.