Evidence map›Paper›PMID 38726722›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024

New-onset atrial fibrillation detected by ambulatory ECG monitoring after transcatheter aortic valve implantation.

Jorge Nuche, Fady Soliman, Jorge Chavarría, Alexis K Okoh, Hugo Alvarado Mora, Isabelle Nault, Madhu K Natarajan, Mark Russo, François Philippon, Josep Rodés-Cabau

Registry-linked trialAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07739316 (Systematic Ambulatory ECG Monitoring Following TAVI), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07739316 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Systematic Ambulatory ECG Monitoring Following TAVI: A Prospective Randomized Trial.

TypeinterventionalSponsorInstitut universitaire de cardiologie et de pneumologie de Québec, University LavalRan2026 to 2028Enrolled754ConditionsAortic Stenosis, Conduction DisturbancesArmsAmbulatory ECG monitoring
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. New-onset or newly detected atrial fibrillation after transcatheter aortic valve implantation?EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jorge NucheQuebec Heart and Lung Institute, Laval University, Quebec City, QC, Canada.
Fady SolimanRutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Jorge ChavarríaMcMaster University, Hamilton, ON, Canada and Hamilton Health Sciences, Hamilton, ON, Canada.
Alexis K OkohRutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
Hugo Alvarado MoraMcMaster University, Hamilton, ON, Canada and Hamilton Health Sciences, Hamilton, ON, Canada.
Isabelle NaultQuebec Heart and Lung Institute, Laval University, Quebec City, QC, Canada.
Madhu K NatarajanMcMaster University, Hamilton, ON, Canada and Hamilton Health Sciences, Hamilton, ON, Canada.
Mark RussoRutgers-Robert Wood Johnson Medical School, New Brunswick, NJ, USA.
François PhilipponQuebec Heart and Lung Institute, Laval University, Quebec City, QC, Canada.
Josep Rodés-CabauQuebec Heart and Lung Institute, Laval University, Quebec City, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the occurrence of subclinical new-onset atrial fibrillation (NOAF) after transcatheter aortic valve implantation (TAVI).

aimsWe aimed to evaluate the incidence, predictors, and clinical impact of subclinical NOAF after TAVI.

methodsThis was a multicentre study, including patients with aortic stenosis (AS) and no previous atrial fibrillation undergoing TAVI, with continuous ambulatory electrocardiogram (AECG) monitoring after TAVI.

resultsA total of 700 patients (79±8 years, 49% female, Society of Thoracic Surgeons score 2.9% [1.9-4.0]) undergoing transarterial TAVI were included (85% balloon-expandable valves). AECG was started 1 (0-1) day after TAVI (monitoring time: 14<span class="eij_ref" contenteditable="false" data-id="26797">12</span><span class="eij_ref" contenteditable="false" data-id="18749">13</span><span class="eij_ref" contenteditable="false" data-id="26798">14</span> days). NOAF was detected in 49 patients (7%), with a median duration of 185 (43-421) minutes (atrial fibrillation burden of 0.7% [0.3-2.8]). Anticoagulation was started in 25 NOAF patients (51%). No differences were found in baseline or procedural characteristics, except for a higher AS severity in the NOAF group (peak gradient: no NOAF: 71.9±23.5 mmHg vs NOAF: 85.2±23.8 mmHg; p=0.024; mean gradient: no NOAF: 44.4±14.7 mmHg vs NOAF: 53.8±16.8 mmHg; p=0.004). In the multivariable analysis, the baseline mean transaortic gradient was associated with a higher risk of NOAF after TAVI (odds ratio 1.04, 95% confidence interval: 1.01-1.06 for each mmHg; p=0.006). There were no differences between groups in all-cause mortality (no NOAF: 4.7% vs NOAF: 0%; p=0.122), stroke (no NOAF: 1.4% vs NOAF: 2.0%; p=0.723), or bleeding (no NOAF: 1.9% vs NOAF: 4.1%; p=0.288) from the 30-day to 1-year follow-up.

conclusionsNOAF detected with AECG occurred in 7% of TAVI recipients and was associated with a higher AS severity. NOAF detection determined the start of anticoagulation therapy in about half of the patients, and it was not associated with an increased risk of clinical events at 1-year follow-up.

Indexed as

Aortic Valve StenosisAtrial FibrillationElectrocardiography, AmbulatoryTranscatheter Aortic Valve ReplacementAgedAged, 80 and overFemaleHumansMaleRisk FactorsTreatment Outcome

Identifiers

PMID38726722
PMCPMC11067725

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.