ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024
Performance and outcomes of the SAPIEN 3 Ultra RESILIA transcatheter heart valve in the OCEAN-TAVI registry.
Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Understanding prosthesis patient mismatch in aortic valve replacement: from pitfalls to clinical impact.Cardiovascular intervention and therapeutics · 2026Review
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- Long-term outcomes after aortic valve replacement in low risk and younger patients: what evidence is available and what is still missing?Journal of thoracic disease · 2026Article
- 7-Year Outcomes of Balloon-Expandable Versus Self-Expanding Valves in Women Undergoing Transcatheter Aortic Valve Replacement.JACC. Asia · 2026Article
- Effective orifice area after Myval and SAPIEN transcatheter valve implantation stratified by flow status: insights from the LANDMARK trial.International journal of cardiology. Heart & vasculature · 2026Article
- Contemporary Management of Aortic Stenosis: Timing of Intervention and Lifetime Valve Management.European journal of clinical investigation · 2026Review
- Temporal trends and long-term clinical outcomes of transcatheter aortic valve implantation.Cardiovascular intervention and therapeutics · 2026Article
- Review
- What Will Define the Next Era of Transcatheter Aortic Valve Replacement: Cost, Volume, and Quality?JACC. Asia · 2026Article
- Review
- One-year outcomes of the RESILIA balloon-expandable transcatheter valve: survival, hemodynamics, and hypoattenuated leaflet thickening.Cardiovascular intervention and therapeutics · 2026Article
- Hemolysis After TAVR Using the Fifth-Generation Balloon-Expandable Valve: Comparison With the Third-Generation Valve.JACC. Asia · 2026Article
- A looming wave of bioprosthetic transcatheter valve failure?-rethinking lifetime management and reintervention in aortic stenosis.Journal of visualized surgery · 2026Article
- Transcatheter Aortic Valve Implantation in Young Patients: Challenges and Perspectives-A Narrative Review.Journal of clinical medicine · 2025Review
- The TAVI Dilemma: Balloon-Expandable or Self-Expanding Transcatheter Heart Valve-Interpreting Current Evidence for Personalized Valve Selection.Journal of clinical medicine · 2025Review
- Index Transcatheter Aortic Valve Expansion After TAV-in-TAV Using a One-Size-Smaller SAPIEN Valve.JACC. Case reports · 2025Article
- Individualized Selection of Valve Intervention Strategies in Aortic Disease Is Key for Better Outcomes.Journal of personalized medicine · 2025Review
- Intra- versus supra-annular self-expanding transcatheter heart valves in small aortic annuli.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Article
- The challenge of interpreting comparative TAVI studies.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025Article
- Co-Occurrence of Aortic Stenosis and Coronary Artery Disease: Facing Challenges Before, During, and After Transcatheter Aortic Valve Replacement.Journal of clinical medicine · 2025Review
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Authors and funding
24 authors.
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Abstract
backgroundData on the performance of the latest-generation SAPIEN 3 Ultra RESILIA (S3UR) valve in patients who undergo transcatheter aortic valve replacement (TAVR) are scarce.
aimsWe aimed to assess the clinical outcomes, including valve performance, of the S3UR.
methodsRegistry data of 618 consecutive patients with S3UR and of a historical pooled cohort of 8,750 patients who had a SAPIEN 3 (S3) valve and underwent TAVR were collected. The clinical outcomes and haemodynamics, including patient-prosthesis mismatch (PPM), were compared between the 2 groups and in a propensity-matched cohort.
resultsThe incidence of in-hospital death, vascular complications, and new pacemaker implantation was similar between the S3UR and the S3 groups (allp>0.05). However, both groups showed significant differences in the degrees of paravalvular leakage (PVL) (none-trivial: 87.0% vs 78.5%, mild: 12.5% vs 20.5%, ≥moderate: 0.5% vs 1.1%; p<0.001) and the incidence of PPM (none: 94.3% vs 85.1%, moderate: 5.2% vs 12.8%, severe: 0.5% vs 2.0%; p<0.001). The prevalence of a mean pressure gradient ≥20 mmHg was significantly lower in the S3UR group (1.6% vs 6.2%; p<0.001). Better haemodynamics were observed with the smaller 20 mm and 23 mm S3UR valves. The results were consistent in a matched cohort of patients with S3UR and with S3 (n=618 patients/group).
conclusionsThe S3UR has equivalent procedural complications to the S3 but with lower rates of PVL and significantly better valve performance. The better valve performance of the S3UR, particularly in smaller valve sizes, overcomes the remaining issue of balloon-expandable valves after TAVR.
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