Evidence map›Paper›PMID 38726597›Full record

ArticleGut microbes

Biofilms and core pathogens shape the tumor microenvironment and immune phenotype in colorectal cancer.

Lasse Kvich, Blaine Gabriel Fritz, Henrike Zschach, Thilde Terkelsen, Hans Raskov, Kathrine Høst-Rasmussen, Morten Ragn Jakobsen, Alexandra Gabriella Gheorghe, Ismail Gögenur, Thomas Bjarnsholt

Abstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  19. Intestinal dysbiosis and colorectal cancer.Chinese medical journal · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lasse KvichCenter for Surgical Science, Department of Surgery, Zealand University Hospital, Region Zealand, Denmark.ORCID 0000-0003-3226-3633
Blaine Gabriel FritzCosterton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-2085-894X
Henrike ZschachCenter for Health Data Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-0045-0573
Thilde TerkelsenCenter for Health Data Science, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0001-9151-3992
Hans RaskovCenter for Surgical Science, Department of Surgery, Zealand University Hospital, Region Zealand, Denmark.ORCID 0000-0001-8126-1920
Kathrine Høst-RasmussenCenter for Surgical Science, Department of Surgery, Zealand University Hospital, Region Zealand, Denmark.
Morten Ragn JakobsenCenter for Surgical Science, Department of Surgery, Zealand University Hospital, Region Zealand, Denmark.
Alexandra Gabriella GheorgheDepartment of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Ismail GögenurCenter for Surgical Science, Department of Surgery, Zealand University Hospital, Region Zealand, Denmark.ORCID 0000-0002-3753-268X
Thomas BjarnsholtCosterton Biofilm Center, Department of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.ORCID 0000-0002-8003-7414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extensive research has explored the role of gut microbiota in colorectal cancer (CRC). Nonetheless, metatranscriptomic studies investigating the

Indexed as

BiofilmsColorectal NeoplasmsGastrointestinal MicrobiomeTumor MicroenvironmentAgedBacteriaBacteroides fragilisCytokinesFemaleFusobacterium nucleatumHumansIn Situ Hybridization, FluorescenceMacrophagesMaleMiddle AgedPhenotypeCytokinesBacteroides fragilisbiofilmsColorectal cancer (CRC)Fusobacterium nucleatumin situ hybridization, fluorescencesequence analysis, RNA

Identifiers

PMID38726597
PMCPMC11093030

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.