Evidence map›Paper›PMID 38726581›Full record

ArticleJournal of preventive medicine and public health = Yebang Uihakhoe chi2024

Factors Associated With Long-term Retention in Antiretroviral Therapy Among People Living With HIV: Evidence From a Tertiary Hospital in Jakarta, Indonesia.

Ifael Yerosias Mauleti, Krishna Adi Wibisana, Djati Prasetio Syamsuridzal, Sri Mulyati, Vivi Lisdawati, Ika Saptarini, Nurhayati, Armedy Ronny Hasugian, Harimat Hendarwan

Abstract read
In one paragraph

Article in Journal of preventive medicine and public health = Yebang Uihakhoe chi, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ifael Yerosias MauletiDepartment of Internal Medicine, Fatmawati General Hospital, Jakarta, Indonesia.
Krishna Adi WibisanaDepartment of Internal Medicine, Fatmawati General Hospital, Jakarta, Indonesia.
Djati Prasetio SyamsuridzalGeneral Practitioner Staff, Fatmawati General Hospital, Jakarta, Indonesia.
Sri MulyatiGeneral Practitioner Staff, Fatmawati General Hospital, Jakarta, Indonesia.
Vivi LisdawatiDirectorate of Human Resources, Education and Research, Fatmawati General Hospital, Jakarta, Indonesia.
Ika SaptariniResearch Center for Preclinical and Clinical Medicine, National Research and Innovation Agency, Bogor, Indonesia.
NurhayatiResearch Center for Preclinical and Clinical Medicine, National Research and Innovation Agency, Bogor, Indonesia.
Armedy Ronny HasugianResearch Center for Preclinical and Clinical Medicine, National Research and Innovation Agency, Bogor, Indonesia.
Harimat HendarwanResearch Center for Preclinical and Clinical Medicine, National Research and Innovation Agency, Bogor, Indonesia.

Funding

Indonesia Endowment Fund for Education
6 · The paper itself

Abstract

objectivesThis study investigated factors associated with the retention of people living with human immunodeficiency virus (HIV) on antiretroviral therapy (ART) during the first 3 years of treatment.

methodsA retrospective study using electronic health records was conducted at a tertiary hospital in Jakarta, Indonesia. Adult HIV-positive patients who started ART from 2010 until 2020 were included. A binary logistic regression model was used to identify factors associated with ART retention in the first 3 years.

resultsIn total, 535 respondents were included in the analysis. The ART retention rates for the first, second, and third years were 83.7%, 79.1%, and 77.2%, respectively. The multivariate analysis revealed a negative association between CD4 count when starting ART and retention. Patients with CD4 counts >200 cells/mL were 0.65 times less likely to have good retention than those with CD4 counts ≤200 cells/mL. The year of starting ART was also significantly associated with retention. Patients who started ART in 2010-2013 or 2014-2016 were less likely to have good retention than those who started ART in 2017-2020, with adjusted odds ratios of 0.52 and 0.40, respectively. Patients who received efavirenz-based therapy were 1.69 times more likely to have good retention than those who received nevirapine (95% confidence interval, 1.05 to 2.72).

conclusionsOur study revealed a decline in ART retention in the third year. The CD4 count, year of enrollment, and an efavirenz-based regimen were significantly associated with retention. Patient engagement has long been a priority in HIV programs, with interventions being implemented to address this issue.

Indexed as

HIV InfectionsTertiary Care CentersAdultAlkynesAnti-HIV AgentsAnti-Retroviral AgentsBenzoxazinesCD4 Lymphocyte CountCyclopropanesDrug MonitoringFemaleHumansIndonesiaLogistic ModelsMaleMedication AdherenceAlkynesAnti-HIV AgentsAnti-Retroviral AgentsBenzoxazinesCyclopropanesefavirenzAcquired immune deficiency syndromeAntiretroviral therapyHuman immunodeficiency virusRetention

Identifiers

PMID38726581
PMCPMC11164604

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.