Evidence map›Paper›PMID 38726419›Full record

ArticleFood science & nutrition2024

Hepatic polypeptide nutrient solution improves high-cholesterol diet-induced rats with nonalcoholic fatty liver disease by activating AMP-activated protein kinase signaling pathway.

Yingying Xiao, Jianan Wang, Ying Zhang, Ting Zhang, Xingzhong Qi, Lei Hou, Zhihong Ma, Feng Xu

Abstract read
In one paragraph

Article in Food science & nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yingying XiaoSchool of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Jianan WangGraduate School Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Ying ZhangSchool of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Ting ZhangExperimental Center Hebei University of Chinese Medicine Shijiazhuang Hebei China.
Xingzhong QiHebei Zhitong Biological Pharmaceutical Co., Ltd. Baoding Hebei China.
Lei HouHebei Zhitong Biological Pharmaceutical Co., Ltd. Baoding Hebei China.
Zhihong MaSchool of Basic Medicine Hebei University of Chinese Medicine Shijiazhuang Hebei China.ORCID https://orcid.org/0000-0001-9989-9578
Feng XuHebei Zhitong Biological Pharmaceutical Co., Ltd. Baoding Hebei China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic polypeptide nutrient solution (HP) is a mixture of hepatoprotective peptides derived from fresh porcine liver with various effects. However, the role and mechanisms of HP in nonalcoholic fatty liver disease (NAFLD) are still not well understood. We investigated the effects of HP NAFLD rats induced by high-cholesterol diet (HCD) and its underlying mechanisms. Rats were provided with HCD for 4 weeks and then received HP or metformin after 2 weeks of HCD feeding. The study found that HP reduced cholesterol and triglyceride levels in rats with NAFLD (all

Indexed as

AMPKhepatic polypeptide nutrient solutionlipid metabolismNAFLD

Identifiers

PMID38726419
PMCPMC11077238

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.