Evidence map›Paper›PMID 38726319›Full record

ArticleJournal of pharmaceutical policy and practice2024

Trends in prescription and cost of Sativex, a cannabinoid-based medicine, in treating patients with multiple sclerosis in England.

Farideh A Javid, Anam Alam, Emily Williams, Sidhra Sajid Malik, Usama Mohayuddin, Syed Shahzad Hasan

Abstract read
In one paragraph

Article in Journal of pharmaceutical policy and practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Farideh A JavidDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.ORCID https://orcid.org/0000-0002-2775-6276
Anam AlamDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Emily WilliamsDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Sidhra Sajid MalikDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Usama MohayuddinDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.
Syed Shahzad HasanDepartment of Pharmacy, School of Applied Sciences, University of Huddersfield, Huddersfield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: Cannabis-based medication has recently been made available in the NHS for reducing pain and spasticity in patients with multiple sclerosis (MS). The currently available preparation of Sativex (nabiximols) contains a combination of botanical cannabis extracts with cannabidiol (CBD) and tetrahydrocannabinol (THC) with almost equal amounts in addition to minor cannabinoids and terpenoids and is delivered via an oro-mucosal spray. The present study aims to examine the use and trends in prescribing cannabinoid-based Sativex to control pain in patients diagnosed with MS. Methods: Primary care prescribing data for cannabinoid-based Sativex (2013-2022) from the Prescription Cost Analysis were extracted and analysed. Linear regression analyses were performed to examine prescription trends and prescription costs (average change per year). Results: There was a general increasing trend in the number of prescriptions each year, from 4.42 items dispensed per 100,000 people in 2013 to 5.15 in 2022. Overall, prescription items for cannabinoid-based Sativex increased by 0.34% per year (95% CI:-3.98, 4.67, Conclusion: The results suggested that cannabinoid-based Sativex should be considered an option due to its effectiveness, acceptable tolerance, and safety profile in the prescribing of Sativex.

Indexed as

and painMSnabiximolsSativexspasticity

Identifiers

PMID38726319
PMCPMC11080669

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.