Evidence map›Paper›PMID 38726288›Full record

ArticleAmerican journal of cancer research2024

Transcriptomic analysis of GITR and GITR ligand reveals cancer immune heterogeneity with implications for GITR targeting.

Peter Moussa, Razelle Kurzrock, Daisuke Nishizaki, Hirotaka Miyashita, Suzanna Lee, Mina Nikanjam, Sarabjot Pabla, Mary K Nesline, Heidi Ko, Jeffrey M Conroy and 3 more

Abstract read
In one paragraph

Article in American journal of cancer research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Peter MoussaDepartment of Medicine, Division of Hematology-Oncology, Moores Cancer Center, UC San Diego La Jolla, CA, The United States.
Razelle KurzrockDepartment of Medicine, Division of Hematology-Oncology, MCW Cancer Center and Genomic Sciences and Precision Medicine Center, Medical College of Wisconsin Milwaukee, WI, The United States.
Daisuke NishizakiDepartment of Medicine, Division of Hematology-Oncology, Moores Cancer Center, UC San Diego La Jolla, CA, The United States.
Hirotaka MiyashitaDepartment of Medicine, Division of Hematology-Oncology, Dartmouth Cancer Center Lebanon, NH, The United States.
Suzanna LeeDepartment of Medicine, Division of Hematology-Oncology, Moores Cancer Center, UC San Diego La Jolla, CA, The United States.
Mina NikanjamDepartment of Medicine, Division of Hematology-Oncology, Moores Cancer Center, UC San Diego La Jolla, CA, The United States.
Sarabjot PablaOmniSeq (Labcorp) Buffalo, NY, The United States.
Mary K NeslineLabcorp Oncology Durham, NC, The United States.
Heidi KoLabcorp Oncology Durham, NC, The United States.
Jeffrey M ConroyOmniSeq (Labcorp) Buffalo, NY, The United States.
Paul DePietroOmniSeq (Labcorp) Buffalo, NY, The United States.
Jason K SicklickDepartment of Surgery, Division of Surgical Oncology, UC San Diego San Diego, CA, The United States.
Shumei KatoDepartment of Medicine, Division of Hematology-Oncology, Moores Cancer Center, UC San Diego La Jolla, CA, The United States.

Funding

SWOG Network Group Operations Center of the NCTNU10CA180888 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PRIMO N. LARA · 2014 to 2026
$152.1M
Medical College of Wisconsin Lead Academic Participating Site RenewalUG1CA233198 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI William H Bradley, Elizabeth M Gore · 2019 to 2026
$5.0M
NCI NIH HHS U10 CA180888NCI NIH HHS UG1 CA233198
6 · The paper itself

Abstract

Glucocorticoid-induced tumor necrosis factor related protein (GITR) is a transmembrane protein expressed mostly on CD25

Indexed as

biomarkersGITRImmunotherapyprecision oncologytranscriptomics

Identifiers

PMID38726288
PMCPMC11076267

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.