Evidence map›Paper›PMID 38726221›Full record

ArticleJournal of cellular signaling2024

Teaching an Old Drug a New Trick: Targeting Treatment Resistance in Genitourinary Cancers.

Karina Aguilar, Anuj K Sharma, Tianyu Yang, Dipen Mehta, Chandramukhi S Panda, Vinata B Lokeshwar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular signaling, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karina AguilarDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, 1410 Laney Walker Blvd., 30912, USA.
Anuj K SharmaDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, 1410 Laney Walker Blvd., 30912, USA.
Tianyu YangDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, 1410 Laney Walker Blvd., 30912, USA.
Dipen MehtaDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, 1410 Laney Walker Blvd., 30912, USA.
Chandramukhi S PandaDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, 1410 Laney Walker Blvd., 30912, USA.
Vinata B LokeshwarDepartment of Biochemistry and Molecular Biology, Medical College of Georgia, Augusta University, Augusta, GA, 1410 Laney Walker Blvd., 30912, USA.

Funding

Novel Biomarkers for the Clinical Management of Bladder CancerR01CA227277 · NCI · AUGUSTA UNIVERSITY · PI LOKESHWAR, VINATA B · 2018 to 2023
$2.2M
Biomarker guided combinations for treating high-risk bladder cancerR01CA283699 · NCI · AUGUSTA UNIVERSITY · PI Vinata B Lokeshwar · 2023 to 2026
$2.1M
NCI NIH HHS R01 CA227277NCI NIH HHS R01 CA283699
6 · The paper itself

Abstract

In the quest for improving the clinical outcome of patients with metastatic genitourinary cancers, including metastatic renal cell carcinoma (mRCC), the emphasis often is on finding new targeted therapies. However, two studies by Jordan

Indexed as

Genitourinary cancerHAS3Hyaluronic acidHymecromone/4-methylumbelliferoneSorafenibUGT-1A9

Identifiers

PMID38726221
PMCPMC11081427

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.