Evidence map›Paper›PMID 38726044›Full record

ArticleACS materials letters2024

Benchmarking Guanidinium Organosulfonate Hydrogen-Bonded Frameworks for Structure Determination of Encapsulated Guests.

Anna Yusov, Alexandra M Dillon, Mohammad T Chaudhry, Justin A Newman, Alfred Y Lee, Michael D Ward

Abstract read
In one paragraph

Article in ACS materials letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Hydrogen-bonded frameworks for conformational analysis of reactive substrates.Chemical communications (Cambridge, England) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anna YusovDepartment of Chemistry and Molecular Design Institute, New York University, New York City, New York 10003, United States.ORCID https://orcid.org/0000-0002-6880-0421
Alexandra M DillonDepartment of Chemistry and Molecular Design Institute, New York University, New York City, New York 10003, United States.ORCID https://orcid.org/0000-0003-4680-0284
Mohammad T ChaudhryAnalytical Research and Development, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States.ORCID https://orcid.org/0000-0002-1482-388X
Justin A NewmanAnalytical Research and Development, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States.ORCID https://orcid.org/0000-0002-2498-1259
Alfred Y LeeAnalytical Research and Development, Merck & Co., Inc., 126 East Lincoln Avenue, Rahway, New Jersey 07065, United States.ORCID https://orcid.org/0000-0003-3684-4101
Michael D WardDepartment of Chemistry and Molecular Design Institute, New York University, New York City, New York 10003, United States.ORCID https://orcid.org/0000-0002-2090-781X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Single crystal X-ray diffraction (SCXRD) is arguably the most definitive method for molecular structure determination, but it is often challenged by compounds that are liquids or oils at room temperature or do not form crystals adequate for analysis. Our laboratory previously reported a simple, cost-effective, single-step crystallization method based on guanidinium organosulfonate (GS) hydrogen bonded frameworks for structure determination of a wide range of encapsulated guest molecules, including assignment of the absolute configuration of chiral centers. Herein, we expand on those results and report a head-to-head comparison of the GS method with adamantoid "molecular chaperones", which have been reported to be useful hosts for structure determination. Inclusion compounds limited to only two GS hosts are characterized by low

Identifiers

PMID38726044
PMCPMC11077584

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.